Neprilysins are highly conserved ectoenzymes that hydrolyze and thus inactivate signaling
peptides in the extracellular space. Herein, we focus on Neprilysin 4 from Drosophila …

Protein-lipid interactions are an essential element of the function of many membrane ion-
channel proteins. These potential interactions should be considered alongside the diversity …

In cardiac myocytes, the type 2a sarco/endoplasmic reticulum Ca-ATPase (SERCA2a) plays
a key role in intracellular Ca regulation. Due to its critical role in heart function, SERCA2a …

The sarco (endo) plasmic reticulum calcium ATPase (SERCA) is an ion transporter that
creates and maintains intracellular calcium stores. SERCA is inhibited or stimulated by …

The clinical management of severe COVID-19 cases is not yet well resolved. Therefore, it is
important to identify and characterize cell signaling pathways involved in virus pathogenesis …

During aging, heart structure and function gradually deteriorate, which subsequently
increases susceptibility to ischemia–reperfusion (IR). Maintenance of Ca2+ homeostasis is …

The endoplasmic reticulum (ER) mitochondria-associated membrane (MAM), or the contact
site between the ER and mitochondria, serves a control station for mitochondrial …