Alzheimer's disease is a progressive neurodegenerative disease most often associated with
memory deficits and cognitive decline, although less common clinical presentations are …

An increasing proportion of cognitive difficulties are recognized to have a functional cause,
the chief clinical indicator of which is internal inconsistency. When these symptoms are …

See Sarazin et al.(doi: 10.1093/brain/aww041) for a scientific commentary on this article.
The advent of the positron emission tomography tracer 18 F-AV1451 provides the unique …

The ordered assembly of tau protein into abnormal filaments is a defining characteristic of
Alzheimer's disease (AD) and other neurodegenerative disorders. It is not known if the …

Introduction A classification framework for posterior cortical atrophy (PCA) is proposed to
improve the uniformity of definition of the syndrome in a variety of research settings. Methods …

In the past 8 years, both the International Working Group (IWG) and the US National Institute
on Aging–Alzheimer's Association have contributed criteria for the diagnosis of Alzheimer's …

A 'frontal variant of Alzheimer's disease'has been described in patients with predominant
behavioural or dysexecutive deficits caused by Alzheimer's disease pathology. The …

Loss of memory is among the first symptoms reported by patients suffering from Alzheimer's
disease (AD) and by their caretakers. Working memory and long-term declarative memory …

Alzheimer disease (AD) is the most common cause of dementia. The prevailing theory of the
underlying pathology assumes amyloid accumulation followed by tau protein aggregation …

Tauopathies are classified according to whether tau deposits predominantly contain tau
isoforms with three or four repeats of the microtubule-binding domain. Those in which four …