To prolong the circulation time of drug, PEGylation has been widely used via the enhanced
permeability and retention (EPR) effect, thereby providing new hope for better treatment …

Present review highlights various drug delivery systems used for delivery of pharmaceutical
agents mainly antibiotics, antineoplastic agents, neuropeptides, and other therapeutic …

Injectable drug nanocarriers have greatly benefited in their clinical development from the
addition of a superficial hydrophilic corona to improve their cargo pharmacokinetics. The …

RNAi (RNA interference)-based technology is emerging as a versatile tool which has been
widely utilized in the treatment of various diseases. siRNA can alter gene expression by …

Artificial, de-novo manufactured materials (with controlled nano-sized characteristics) have
been progressively used by neuroscientists during the last several decades. The …

Lack of safe and effective delivery vehicle is the main obstacle for siRNA mediated cancer
therapy. In this study, we synthesized a pH-sensitive polymer of PEG grafted carboxymethyl …

Several researchers have reported the use of cholesterol-based carriers in drug delivery.
The presence of cholesterol in cell membranes and its wide distribution in the body has led …

All-Trans Retinoic Acid (ATRA) is the most active metabolite of vitamin A. It is critically
involved in the regulation of multiple processes, such as cell differentiation and apoptosis …

Cancer remains a deadly disease for effective treatment. Although anomalous tumor
microenvironment is now widely exploited for targeted chemotherapy, safe and efficacious …

Formulations of cationic liposomes and polymers readily self-assemble by electrostatic
interactions with siRNA to form cationic nanoparticles which achieve efficient transfection …