[HTML][HTML] Roles of PI3K/AKT/GSK3 pathway involved in psychiatric illnesses
S Matsuda, Y Ikeda, M Murakami, Y Nakagawa, A Tsuji… - Diseases, 2019 - mdpi.com
Psychiatric illnesses may be qualified to the cellular impairments of the function for survival
or death in neurons, which may consequently appear as abnormalities in the neuroplasticity …
or death in neurons, which may consequently appear as abnormalities in the neuroplasticity …
Metabolic hormone action in the VTA: Reward-directed behavior and mechanistic insights
CE Geisler, MR Hayes - Physiology & behavior, 2023 - Elsevier
Dysfunctional signaling in midbrain reward circuits perpetuates diseases characterized by
compulsive overconsumption of rewarding substances such as substance abuse, binge …
compulsive overconsumption of rewarding substances such as substance abuse, binge …
[HTML][HTML] Habitual daily intake of a sweet and fatty snack modulates reward processing in humans
SE Thanarajah, AG DiFeliceantonio, K Albus… - Cell metabolism, 2023 - cell.com
Western diets rich in fat and sugar promote excess calorie intake and weight gain; however,
the underlying mechanisms are unclear. Despite a well-documented association between …
the underlying mechanisms are unclear. Despite a well-documented association between …
Pathophysiology linking depression and type 2 diabetes: psychotherapy, physical exercise, and fecal microbiome transplantation as damage control
Diabetes increases the likelihood of developing depression and vice versa. Research on
this bidirectional association has somewhat managed to delineate the interplay among …
this bidirectional association has somewhat managed to delineate the interplay among …
[HTML][HTML] Nutrient-mediated perception and signalling in human metabolism: a perspective of nutrigenomics
The interaction between selective nutrients and linked genes involving a specific organ
reveals the genetic make-up of an individual in response to a particular nutrient. The …
reveals the genetic make-up of an individual in response to a particular nutrient. The …
[HTML][HTML] High-fat diet-induced weight gain, behavioral deficits, and dopamine changes in young C57BL/6J mice
J Han, P Nepal, A Odelade, FD Freely, DM Belton… - Frontiers in …, 2021 - frontiersin.org
Chronic exposure to a high-fat diet (HFD) may predispose individuals to neuropathologies
and behavioral deficits. The objective of this study was to determine the temporal effects of a …
and behavioral deficits. The objective of this study was to determine the temporal effects of a …
[HTML][HTML] Food memory circuits regulate eating and energy balance
TR Pardo-Garcia, K Gu, RKR Woerner, M Dus - Current Biology, 2023 - cell.com
In mammals, learning circuits play an essential role in energy balance by creating
associations between sensory cues and the rewarding qualities of food. This process is …
associations between sensory cues and the rewarding qualities of food. This process is …
Appetitive traits as targets for weight loss: The role of food cue responsiveness and satiety responsiveness
Individuals with overweight or obesity (OW/OB) are at increased risk for significant physical
and psychological comorbidities. The current treatment for OW/OB is behavioral weight loss …
and psychological comorbidities. The current treatment for OW/OB is behavioral weight loss …
Neurological and metabolic related pathophysiologies and treatment of comorbid diabetes with depression
S Li, D Yang, X Zhou, L Chen, L Liu… - CNS Neuroscience …, 2024 - Wiley Online Library
Background The comorbidity between diabetes mellitus and depression was revealed, and
diabetes mellitus increased the prevalence of depressive disorder, which ranked 13th in the …
diabetes mellitus increased the prevalence of depressive disorder, which ranked 13th in the …
[HTML][HTML] Brain imaging of taste perception in obesity: a review
Abstract Purpose of Review We summarize neuroimaging findings related to processing of
taste (fat, salt, umami, bitter, and sour) in the brain and how they influence hedonic …
taste (fat, salt, umami, bitter, and sour) in the brain and how they influence hedonic …