Targeting integrin pathways: mechanisms and advances in therapy
X Pang, X He, Z Qiu, H Zhang, R Xie, Z Liu… - … and Targeted Therapy, 2023 - nature.com
Integrins are considered the main cell-adhesion transmembrane receptors that play
multifaceted roles as extracellular matrix (ECM)-cytoskeletal linkers and transducers in …
multifaceted roles as extracellular matrix (ECM)-cytoskeletal linkers and transducers in …
2021 ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure: Developed by the Task Force for the diagnosis and treatment of acute and …
The aim of this ESC Guideline is to help health professionals manage people with heart
failure (HF) according to the best available evidence. Fortunately, we now have a wealth of …
failure (HF) according to the best available evidence. Fortunately, we now have a wealth of …
2021 ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure: Developed by the Task Force for the diagnosis and treatment of acute and …
Authors/Task Force Members:… - European journal of …, 2022 - Wiley Online Library
Abstract Document Reviewers: Rudolf A. de Boer (CPG Review Coordinator)(Netherlands),
P. Christian Schulze (CPG Review Coordinator)(Germany), Magdy Abdelhamid (Egypt) …
P. Christian Schulze (CPG Review Coordinator)(Germany), Magdy Abdelhamid (Egypt) …
Integrating single-cell and spatial transcriptomics to elucidate intercellular tissue dynamics
Single-cell RNA sequencing (scRNA-seq) identifies cell subpopulations within tissue but
does not capture their spatial distribution nor reveal local networks of intercellular …
does not capture their spatial distribution nor reveal local networks of intercellular …
Obesity and cardiovascular disease: a scientific statement from the American Heart Association
TM Powell-Wiley, P Poirier, LE Burke, JP Després… - Circulation, 2021 - Am Heart Assoc
The global obesity epidemic is well established, with increases in obesity prevalence for
most countries since the 1980s. Obesity contributes directly to incident cardiovascular risk …
most countries since the 1980s. Obesity contributes directly to incident cardiovascular risk …
Heart failure with mid-range or mildly reduced ejection fraction
G Savarese, D Stolfo, G Sinagra, LH Lund - Nature Reviews Cardiology, 2022 - nature.com
Left ventricular ejection fraction (EF) remains the major parameter for diagnosis,
phenotyping, prognosis and treatment decisions in heart failure. The 2016 ESC heart failure …
phenotyping, prognosis and treatment decisions in heart failure. The 2016 ESC heart failure …
2020 ESC Guidelines on sports cardiology and exercise in patients with cardiovascular disease: The Task Force on sports cardiology and exercise in patients with …
or therapeutic medical strategies. However, the ESC Guidelines do not override in any way
whatsoever the individual responsibility of health professionals to make appropriate and …
whatsoever the individual responsibility of health professionals to make appropriate and …
Outcomes of cardiovascular magnetic resonance imaging in patients recently recovered from coronavirus disease 2019 (COVID-19)
VO Puntmann, ML Carerj, I Wieters, M Fahim… - JAMA …, 2020 - jamanetwork.com
Importance Coronavirus disease 2019 (COVID-19) continues to cause considerable
morbidity and mortality worldwide. Case reports of hospitalized patients suggest that COVID …
morbidity and mortality worldwide. Case reports of hospitalized patients suggest that COVID …
Heart Failure With Recovered Left Ventricular Ejection Fraction: JACC Scientific Expert Panel
JE Wilcox, JC Fang, KB Margulies, DL Mann - Journal of the American …, 2020 - jacc.org
Reverse left ventricular (LV) remodeling and recovery of LV function are associated with
improved clinical outcomes in patients with heart failure with reduced ejection fraction. A …
improved clinical outcomes in patients with heart failure with reduced ejection fraction. A …
Desmoplakin cardiomyopathy, a fibrotic and inflammatory form of cardiomyopathy distinct from typical dilated or arrhythmogenic right ventricular cardiomyopathy
ED Smith, NK Lakdawala, N Papoutsidakis, G Aubert… - Circulation, 2020 - Am Heart Assoc
Background: Mutations in desmoplakin (DSP), the primary force transducer between cardiac
desmosomes and intermediate filaments, cause an arrhythmogenic form of cardiomyopathy …
desmosomes and intermediate filaments, cause an arrhythmogenic form of cardiomyopathy …