Diabetic retinopathy: vascular and inflammatory disease

F Semeraro, A Cancarini, R dell'Omo… - Journal of diabetes …, 2015 - Wiley Online Library
Diabetic retinopathy (DR) is the leading cause of visual impairment in the working‐age
population of the Western world. The pathogenesis of DR is complex and several vascular …

Role of cytokines and chemokines in angiogenesis in a tumor context

M Geindreau, M Bruchard, F Vegran - Cancers, 2022 - mdpi.com
Simple Summary Tumor growth in solid cancers requires adequate nutrient and oxygen
supply, provided by blood vessels created by angiogenesis. Numerous studies have …

Cancer-associated fibroblast-derived WNT2 increases tumor angiogenesis in colon cancer

D Unterleuthner, P Neuhold, K Schwarz, L Janker… - Angiogenesis, 2020 - Springer
WNT2 acts as a pro-angiogenic factor in placental vascularization and increases
angiogenesis in liver sinusoidal endothelial cells (ECs) and other ECs. Increased WNT2 …

[HTML][HTML] VEGFR1 signaling in retinal angiogenesis and microinflammation

A Uemura, M Fruttiger, PA d'Amore, S De Falco… - Progress in retinal and …, 2021 - Elsevier
Five vascular endothelial growth factor receptor (VEGFR) ligands (VEGF-A,-B,–C,-D, and
placental growth factor [PlGF]) constitute the VEGF family. VEGF-A binds VEGF receptors 1 …

Vascular endothelial growth factors and angiogenesis in eye disease

AN Witmer, G Vrensen, CJF Van Noorden… - Progress in retinal and …, 2003 - Elsevier
The vascular endothelial growth factor (VEGF) family of growth factors controls pathological
angiogenesis and increased vascular permeability in important eye diseases such as …

The discovery of placenta growth factor and its biological activity

S De Falco - Experimental & molecular medicine, 2012 - nature.com
Angiogenesis is a complex biological phenomenon crucial for a correct embryonic
development and for post-natal growth. In adult life, it is a tightly regulated process confined …

FLT1 and its ligands VEGFB and PlGF: drug targets for anti-angiogenic therapy?

C Fischer, M Mazzone, B Jonckx, P Carmeliet - Nature Reviews Cancer, 2008 - nature.com
Less than 5 years ago, it was still not clear whether anti-angiogenic drugs would prove
successful in the clinic. After numerous patients with cancer or age-related macular …

Current and emerging therapies for corneal neovascularization

D Roshandel, M Eslani, A Baradaran-Rafii… - The ocular …, 2018 - Elsevier
The cornea is unique because of its complete avascularity. Corneal neovascularization
(CNV) can result from a variety of etiologies including contact lens wear; corneal infections; …

Regulation of vascular growth and function in the human placenta

GJ Burton, DS Charnock-Jones, E Jauniaux - Reproduction, 2009 - rep.bioscientifica.com
During the course of 9 months, the human placenta develops into a highly vascular organ.
Vasculogenesis starts during the third week post-conception. Hemangioblastic cell cords …

Aspects of human fetoplacental vasculogenesis and angiogenesis. II. Changes during normal pregnancy

P Kaufmann, TM Mayhew, DS Charnock-Jones - Placenta, 2004 - Elsevier
In this second review, we describe the main morphological events which accompany the
development of the fetoplacental vascular system throughout normal human pregnancy and …