Vascular mechanotransduction
This review aims to survey the current state of mechanotransduction in vascular smooth
muscle cells (VSMCs) and endothelial cells (ECs), including their sensing of mechanical …
muscle cells (VSMCs) and endothelial cells (ECs), including their sensing of mechanical …
Matrix metalloproteinases, vascular remodeling, and vascular disease
X Wang, RA Khalil - Advances in pharmacology, 2018 - Elsevier
Matrix metalloproteinases (MMPs) are a family of zinc-dependent endopeptidases that
degrade various proteins in the extracellular matrix (ECM). Typically, MMPs have a …
degrade various proteins in the extracellular matrix (ECM). Typically, MMPs have a …
Ischemia/reperfusion injury following acute myocardial infarction: a critical issue for clinicians and forensic pathologists
M Neri, I Riezzo, N Pascale, C Pomara… - Mediators of …, 2017 - Wiley Online Library
Acute myocardial infarction (AMI) is a leading cause of morbidity and mortality. Reperfusion
strategies are the current standard therapy for AMI. However, they may result in paradoxical …
strategies are the current standard therapy for AMI. However, they may result in paradoxical …
Relaxin family peptides and their receptors
RAD Bathgate, ML Halls… - Physiological …, 2013 - journals.physiology.org
There are seven relaxin family peptides that are all structurally related to insulin. Relaxin has
many roles in female and male reproduction, as a neuropeptide in the central nervous …
many roles in female and male reproduction, as a neuropeptide in the central nervous …
Structure and function of matrix metalloproteinases and TIMPs
H Nagase, R Visse, G Murphy - Cardiovascular research, 2006 - academic.oup.com
Matrix metalloproteinases (MMPs), also called matrixins, function in the extracellular
environment of cells and degrade both matrix and non-matrix proteins. They play central …
environment of cells and degrade both matrix and non-matrix proteins. They play central …
Matrix metalloproteinases and the regulation of tissue remodelling
Matrix metalloproteinases (MMPs) were discovered because of their role in amphibian
metamorphosis, yet they have attracted more attention because of their roles in disease …
metamorphosis, yet they have attracted more attention because of their roles in disease …
Matrix metalloproteinases in vascular remodeling and atherogenesis: the good, the bad, and the ugly
ZS Galis, JJ Khatri - Circulation research, 2002 - Am Heart Assoc
Vascular remodeling, defined as any enduring change in the size and/or composition of an
adult blood vessel, allows adaptation and repair. On the other hand, inappropriate …
adult blood vessel, allows adaptation and repair. On the other hand, inappropriate …
[HTML][HTML] Unbiased analysis of senescence associated secretory phenotype (SASP) to identify common components following different genotoxic stresses
S Özcan, N Alessio, MB Acar, E Mert, F Omerli… - Aging (Albany …, 2016 - ncbi.nlm.nih.gov
Senescent cells secrete senescence-associated secretory phenotype (SASP) proteins to
carry out several functions, such as sensitizing surrounding cells to senesce; …
carry out several functions, such as sensitizing surrounding cells to senesce; …
Matrix metalloproteinases: effectors of development and normal physiology
TH Vu, Z Werb - Genes & development, 2000 - genesdev.cshlp.org
The matrix metalloproteinase (MMP) family of extracellular proteinases regulates
development and physiologic events. Genetic analyses using transgenic mice that have …
development and physiologic events. Genetic analyses using transgenic mice that have …
Matrix metalloproteinases and their multiple roles in neurodegenerative diseases
GA Rosenberg - The Lancet Neurology, 2009 - thelancet.com
Matrix metalloproteinases (MMPs) and proteins containing a disintegrin and
metalloproteinase domain (ADAM) are important in neuroinflammation, and recent studies …
metalloproteinase domain (ADAM) are important in neuroinflammation, and recent studies …