[HTML][HTML] The interconnected mechanisms of oxidative stress and neuroinflammation in epilepsy
ALM Parsons, EMV Bucknor, E Castroflorio, TR Soares… - Antioxidants, 2022 - mdpi.com
One of the most important characteristics of the brain compared to other organs is its
elevated metabolic demand. Consequently, neurons consume high quantities of oxygen …
elevated metabolic demand. Consequently, neurons consume high quantities of oxygen …
Human neuronal maturation comes of age: cellular mechanisms and species differences
JL Wallace, AA Pollen - Nature Reviews Neuroscience, 2024 - nature.com
The delayed and prolonged postmitotic maturation of human neurons, compared with
neurons from other species, may contribute to human-specific cognitive abilities and …
neurons from other species, may contribute to human-specific cognitive abilities and …
[HTML][HTML] Connectomes across development reveal principles of brain maturation
An animal's nervous system changes as its body grows from birth to adulthood and its
behaviours mature,,,,,,–. The form and extent of circuit remodelling across the connectome is …
behaviours mature,,,,,,–. The form and extent of circuit remodelling across the connectome is …
[HTML][HTML] Neurohybrid memristive CMOS-integrated systems for biosensors and neuroprosthetics
Here we provide a perspective concept of neurohybrid memristive chip based on the
combination of living neural networks cultivated in microfluidic/microelectrode system, metal …
combination of living neural networks cultivated in microfluidic/microelectrode system, metal …
Keeping your brain in balance: Homeostatic regulation of network function
W Wen, GG Turrigiano - Annual Review of Neuroscience, 2024 - annualreviews.org
To perform computations with the efficiency necessary for animal survival, neocortical
microcircuits must be capable of reconfiguring in response to experience, while carefully …
microcircuits must be capable of reconfiguring in response to experience, while carefully …
[HTML][HTML] Balance of activity during a critical period tunes a developing network
I Hunter, B Coulson, T Pettini, JJ Davies, J Parkin… - Elife, 2024 - elifesciences.org
Developing neural circuits are influenced by activity and are especially sensitive to changes
in activity during critical periods (CPs) of development. Changes occurring during a CP often …
in activity during critical periods (CPs) of development. Changes occurring during a CP often …
miR‐124‐dependent tagging of synapses by synaptopodin enables input‐specific homeostatic plasticity
S Dubes, A Soula, S Benquet, B Tessier… - The EMBO …, 2022 - embopress.org
Homeostatic synaptic plasticity is a process by which neurons adjust their synaptic strength
to compensate for perturbations in neuronal activity. Whether the highly diverse synapses on …
to compensate for perturbations in neuronal activity. Whether the highly diverse synapses on …
[HTML][HTML] AUTS2 Gene: Keys to Understanding the Pathogenesis of Neurodevelopmental Disorders
K Hori, K Shimaoka, M Hoshino - Cells, 2021 - mdpi.com
Neurodevelopmental disorders (NDDs), including autism spectrum disorders (ASD) and
intellectual disability (ID), are a large group of neuropsychiatric illnesses that occur during …
intellectual disability (ID), are a large group of neuropsychiatric illnesses that occur during …
[HTML][HTML] Activity-dependent plasticity of axo-axonic synapses at the axon initial segment
The activity-dependent rules that govern the wiring of GABAergic interneurons are not well
understood. Chandelier cells (ChCs) are a type of GABAergic interneuron that control …
understood. Chandelier cells (ChCs) are a type of GABAergic interneuron that control …
Homeostatic plasticity in the retina
MJ Fitzpatrick, D Kerschensteiner - Progress in Retinal and Eye Research, 2023 - Elsevier
Vision begins in the retina, whose intricate neural circuits extract salient features of the
environment from the light entering our eyes. Neurodegenerative diseases of the retina (eg …
environment from the light entering our eyes. Neurodegenerative diseases of the retina (eg …