Measuring viscoelasticity of soft biological samples using atomic force microscopy

YM Efremov, T Okajima, A Raman - Soft matter, 2020 - pubs.rsc.org
Mechanical properties play important roles at different scales in biology. At the level of a
single cell, the mechanical properties mediate mechanosensing and mechanotransduction …

Force measurements with the atomic force microscope: Technique, interpretation and applications

HJ Butt, B Cappella, M Kappl - Surface science reports, 2005 - Elsevier
The atomic force microscope (AFM) is not only a tool to image the topography of solid
surfaces at high resolution. It can also be used to measure force-versus-distance curves …

High-frequency microrheology reveals cytoskeleton dynamics in living cells

A Rigato, A Miyagi, S Scheuring, F Rico - Nature physics, 2017 - nature.com
Living cells are viscoelastic materials, dominated by an elastic response on timescales
longer than a millisecond. On shorter timescales, the dynamics of individual cytoskeleton …

Mechanotransduction across the cell surface and through the cytoskeleton

N Wang, JP Butler, DE Ingber - Science, 1993 - science.org
Mechanical stresses were applied directly to cell surface receptors with a magnetic twisting
device. The extracellular matrix receptor, integrin β1, induced focal adhesion formation and …

Cellular tensegrity: defining new rules of biological design that govern the cytoskeleton

DE Ingber - Journal of cell science, 1993 - journals.biologists.com
Cellular tensegrity: defining new rules of biological design that govern the cytoskeleton | Journal
of Cell Science | The Company of Biologists Skip to Main Content Advertisement The Company …

[HTML][HTML] The optical stretcher: a novel laser tool to micromanipulate cells

J Guck, R Ananthakrishnan, H Mahmood, TJ Moon… - Biophysical journal, 2001 - cell.com
When a dielectric object is placed between two opposed, nonfocused laser beams, the total
force acting on the object is zero but the surface forces are additive, thus leading to a …

[HTML][HTML] Drug-induced changes of cytoskeletal structure and mechanics in fibroblasts: an atomic force microscopy study

C Rotsch, M Radmacher - Biophysical journal, 2000 - cell.com
The effect of various drugs affecting the integrity of different components of the cytoskeleton
on the elasticity of two fibroblast cell lines was investigated by elasticity measurements with …

Mechanical models for living cells—a review

CT Lim, EH Zhou, ST Quek - Journal of biomechanics, 2006 - Elsevier
As physical entities, living cells possess structural and physical properties that enable them
to withstand the physiological environment as well as mechanical stimuli occurring within …

Measuring the viscoelastic properties of human platelets with the atomic force microscope

M Radmacher, M Fritz, CM Kacher, JP Cleveland… - Biophysical journal, 1996 - cell.com
We have measured force curves as a function of the lateral position on top of human
platelets with the atomic force microscope. These force curves show the indentation of the …

Stretch‐activated single ion channel currents in tissue‐cultured embryonic chick skeletal muscle.

F Guharay, F Sachs - The Journal of physiology, 1984 - Wiley Online Library
The membrane of tissue‐cultured chick pectoral muscle contains an ionic channel which is
activated by membrane stretch. Nicotinic channels and Ca2+‐activated K+ channels are not …