Transdermal drug delivery refers to a means of delivering drugs through the surface of the
skin for local or systemic treatment. The drug functions after absorption through the skin into …

Niosomes are vesicular nanocarriers and are receiving much attention as potential
transdermal drug delivery systems due to properties such as enhanced drug penetration …

Targeted drug delivery systems using nanocarriers offer a versatile platform for breast
cancer treatment; however, a robust, CD44-targeted niosomal formulation has not been …

In designing a new drug, considering the preferred route of administration, various
requirements must be fulfilled. Active molecules pharmacokinetics should be reliable with a …

Simvastatin (SMV), a cholesterol-lowering agent, has antioxidant and anti-inflammatory
effects. Nevertheless, the oral use of SMV is linked with poor systemic bioavailability owing …

Niosomes, as a kind of drug delivery system, is widely used for the topical delivery of
lipophilic drugs. Optimization of niosomes plays an essential role in enhancing their …

Simvastatin (SIM) is a HMG-CoA reductase inhibitor employed in the management of
hyperlipidemia. However, its low bioavailability limits its clinical efficacy. The objective of this …

Objective The objective of this study was to use nano-niosomal formulations to deliver
simvastatin as a poor-water soluble drug into breast cancer cells. Significance Our study …

Flibanserin (FLB) is a multifunctional serotonergic agent that was recently approved by the
FDA for the oral treatment of premenopausal women with hypoactive sexual desire disorder …

Transdermal drug delivery (TDD) has recently emerged as an effective alternative to oral
and injection administration because of its less invasiveness, low rejection rate, and …