Hereditary multiple exostoses (HMEs) syndrome, also known as multiple osteochondromas,
represents a rare and severe human skeletal disorder. The disease is characterized by …

Hereditary multiple osteochondromas (HMO), previously called hereditary multiple
exostoses (HME), is characterized by growths of multiple osteochondromas, benign …

Heparan sulfate is a highly modified O-linked glycan that performs diverse physiological
roles in animal tissues. Though quickly modified, it is initially synthesised as a …

Multiple Osteochondromatosis (MO, MIM 133700 & 133701), an autosomal dominant O-
glycosylation disorder (EXT1/EXT2-CDG), can be associated with a reduction in skeletal …

This study is aimed at investigating the clinical and genetic characteristics of 244 unrelated
probands diagnosed with multiple osteochondromas (MO). The diagnosis of MO typically …

Numerous proteins are glycosylated with monosaccharides and/or oligosaccharide
structures, also termed glycans, attached to the polypeptide chain. Most extracellular …

Background: HMO (Hereditary Multiple Osteochondroma), an uncommon autosomal
dominant disorder, is characterized by the development of multiple osteochondromas, which …

Multiple osteochondromas (MO), the most common type of benign bone tumor, is an
autosomal dominant skeletal disorder characterized by multiple cartilage-capped bony …

Osteochondromatosis is a benign proliferative disorder characterized by cartilage‐capped
bony protuberances. In humans and most mammals, variants in the EXT1 or EXT2 gene are …

The aim of the present study was to investigate the molecular characteristics of hereditary
multiple osteochondromas (HMO) in a subset of Jordanian patients with a focus on the …