Neurotrophic factors and neuroplasticity pathways in the pathophysiology and treatment of depression

MJF Levy, F Boulle, HW Steinbusch… - …, 2018 - Springer
Depression is a major health problem with a high prevalence and a heavy socioeconomic
burden in western societies. It is associated with atrophy and impaired functioning of cortico …

Neuroimaging biomarkers as predictors of treatment outcome in major depressive disorder

TM Fonseka, GM MacQueen, SH Kennedy - Journal of affective disorders, 2018 - Elsevier
Background Current practice for selecting pharmacological and non-pharmacological
antidepressant treatments has yielded low response and remission rates in Major …

Depression and episodic memory across the adult lifespan: A meta-analytic review.

TA James, S Weiss-Cowie, Z Hopton… - Psychological …, 2021 - psycnet.apa.org
Episodic memory deficits have increasingly been recognized as a cognitive feature of
depression. To quantify these deficits and determine how they are moderated by various …

[HTML][HTML] MRI predictors of pharmacotherapy response in major depressive disorder

AR Gerlach, HT Karim, M Pecina, O Ajilore… - NeuroImage: Clinical, 2022 - Elsevier
Major depressive disorder is among the most prevalent psychiatric disorders, exacting a
substantial personal, social, and economic toll. Antidepressant treatment typically involves …

Diagnostic and therapeutic utility of neuroimaging in depression: an overview

T Wise, AJ Cleare, A Herane, AH Young… - … disease and treatment, 2014 - Taylor & Francis
A growing number of studies have used neuroimaging to further our understanding of how
brain structure and function are altered in major depression. More recently, these techniques …

Exercise leads to better clinical outcomes in those receiving medication plus cognitive behavioral therapy for major depressive disorder

J Gourgouvelis, P Yielder, ST Clarke… - Frontiers in …, 2018 - frontiersin.org
Objective The aim of this study is to investigate the effects of exercise as an add-on therapy
with antidepressant medication and cognitive behavioral group therapy (CBGT) on treatment …

Default mode network deactivation during emotion processing predicts early antidepressant response

M Spies, C Kraus, N Geissberger, B Auer… - Translational …, 2017 - nature.com
Several previous functional magnetic resonance imaging (fMRI) studies have demonstrated
the predictive value of brain activity during emotion processing for antidepressant response …

The Canadian biomarker integration network in depression (CAN-BIND): magnetic resonance imaging protocols

GM MacQueen, S Hassel, SR Arnott, J Addington… - Journal of Psychiatry and …, 2019 - jpn.ca
Studies of clinical populations that combine MRI data generated at multiple sites are
increasingly common. The Canadian Biomarker Integration Network in Depression (CAN …

Baseline brain perfusion and brain structure in patients with major depression: a multimodal magnetic resonance imaging study

N Vasic, ND Wolf, G Grön, Z Sosic-Vasic… - Journal of Psychiatry and …, 2015 - jpn.ca
Background: Abnormal regional cerebral blood flow (rCBF) and grey matter volume have
been frequently reported in patients with major depressive disorder (MDD). However, it is …

Ensemble learning for early‐response prediction of antidepressant treatment in major depressive disorder

C Pei, Y Sun, J Zhu, X Wang, Y Zhang… - Journal of Magnetic …, 2020 - Wiley Online Library
Background In order to reduce unsuccessful treatment trials for depression, neuroimaging
and genetic information can be considered as biomarkers. Together with machine‐learning …