New insights into the role of NLRP3 inflammasome in pathogenesis and treatment of chronic obstructive pulmonary disease

J Zhang, Q Xu, W Sun, X Zhou, D Fu… - Journal of inflammation …, 2021 - Taylor & Francis
Chronic obstructive pulmonary disease (COPD) is an inflammatory lung disease
characterized by chronic airway obstruction and emphysema. Accumulating studies have …

Association between single-nucleotide polymorphism of cytokines genes and chronic obstructive pulmonary disease: A systematic review and meta-analysis

A Masjedy, M Salesi, A Ahmadi, J Salimian… - Cytokine, 2023 - Elsevier
Chronic obstructive pulmonary disease (COPD) is a common chronic inflammatory disease
with high morbidity and mortality rates worldwide. Cytokines, which are the main regulators …

Guidelines for diagnosis and management of chronic obstructive pulmonary disease: Joint ICS/NCCP (I) recommendations

D Gupta, R Agarwal, AN Aggarwal, VN Maturu… - Lung India, 2013 - journals.lww.com
Chronic obstructive pulmonary disease (COPD) is a major public health problem in India.
Although several International guidelines for diagnosis and management of COPD are …

[HTML][HTML] High-sensitivity C-reactive protein and tumor necrosis factor alpha in pseudoexfoliation syndrome

R Sorkhabi, A Ghorbanihaghjo, M Ahoor… - Oman medical …, 2013 - ncbi.nlm.nih.gov
Objectives The purpose of the present study was to determine the alterations in high-
sensitivity C-reactive protein and Tumor Necrosis factor alpha levels in the blood serum of …

Association between the IL1B, IL1RN polymorphisms and COPD risk: A meta-analysis

ZK Xie, QP Huang, J Huang, ZF Xie - Scientific reports, 2014 - nature.com
Abstract The interleukin-1 (IL-1) gene polymorphisms have been implicated in chronic
obstructive pulmonary disease (COPD) risk, but results are controversial. We aimed to …

Association between chronic obstructive pulmonary disease and interleukins gene variants: A systematic review and meta-analysis

A Ahmadi, H Ghaedi, J Salimian, SA Jamalkandi… - Cytokine, 2019 - Elsevier
Interleukins are cytokines involved in systemic inflammation and immune system regulation.
Many studies have investigated the association between common genetic variations in …

Immune-related gene polymorphisms in pulmonary diseases

DP Singh, P Bagam, MK Sahoo, S Batra - Toxicology, 2017 - Elsevier
Between the DNA sequences of two randomly-selected human genomes, which consist of
over 3 billion base pairs and twenty five thousand genes, there exists only 0.1% variation …

Association between TNF-α− 308 G/A polymorphism and COPD susceptibility: a meta-analysis update

L Zhang, H Gu, Y Gu, X Zeng - International journal of chronic …, 2016 - Taylor & Francis
Background and objective The association between TNF-α− 308 G/A polymorphism and
COPD remains controversial due to insufficiently strict study designs and small group sizes …

Influence of proinflammatory cytokine gene polymorphisms on the risk of COPD and the levels of plasma protein

E Ambrocio-Ortiz, G Pérez-Rubio, E Abarca-Rojano… - Cytokine, 2018 - Elsevier
Introduction Chronic obstructive pulmonary disease (COPD) is a complex and multifactorial
disease involving systemic inflammation. Although certain genetic components have been …

Heterogeneity of chronic obstructive pulmonary disease: from phenotype to genotype

X Chen, X Xu, F Xiao - Frontiers of medicine, 2013 - Springer
Chronic obstructive pulmonary disease (COPD) is one of the leading causes of morbidity
and mortality throughout the world and is mainly characterized by persistent airflow …