Purinergic signaling plays important roles in control of vascular tone and remodeling. There
is dual control of vascular tone by ATP released as a cotransmitter with noradrenaline from …

Preeclampsia is a syndrome characterized by hypertension during pregnancy, which is a
leading cause of morbidity and mortality in both mother and newborn in developing …

Pre-eclampsia is a serious complication of pregnancy that can affect both maternal and fetal
outcomes. Early-onset pre-eclampsia (EOPET) is a severe form of pre-eclampsia that is …

There are nineteen different receptor proteins for adenosine, adenine and uridine
nucleotides, and nucleotide sugars, belonging to three families of G protein-coupled …

Recently it has become clear that the cost associated with the Warburg effect, which is
inefficient production of ATP, is offset by selective advantages that are produced by resultant …

Insulin resistance is characteristic of pregnancies where the mother shows metabolic
alterations, such as preeclampsia (PE) and gestational diabetes mellitus (GDM), or …

Placentas from gestational diabetes mellitus (GDM) are often hypervascularized; however,
participation of vascular endothelial growth factor (VEGF) and its receptors in this placental …

Adenosine is an endogenous nucleoside with pleiotropic effects in different physiological
processes including circulation, renal blood flow, immune function, or glucose homeostasis …

Abnormal placental angiogenesis is associated with the occurrence of intrauterine growth
restriction (IUGR) in piglets, and effective treatment strategies against this occurrence …

Cerebral complications in preeclampsia contribute substantially to maternal mortality and
morbidity. There is a lack of reliable and accessible predictors for preeclampsia-related …