Purinergic signaling and blood vessels in health and disease
G Burnstock, V Ralevic - Pharmacological reviews, 2014 - ASPET
Purinergic signaling plays important roles in control of vascular tone and remodeling. There
is dual control of vascular tone by ATP released as a cotransmitter with noradrenaline from …
is dual control of vascular tone by ATP released as a cotransmitter with noradrenaline from …
[HTML][HTML] Role of extracellular vesicles and microRNAs on dysfunctional angiogenesis during preeclamptic pregnancies
CA Escudero, K Herlitz, F Troncoso, J Acurio… - Frontiers in …, 2016 - frontiersin.org
Preeclampsia is a syndrome characterized by hypertension during pregnancy, which is a
leading cause of morbidity and mortality in both mother and newborn in developing …
leading cause of morbidity and mortality in both mother and newborn in developing …
Widespread DNA hypomethylation at gene enhancer regions in placentas associated with early-onset pre-eclampsia
Pre-eclampsia is a serious complication of pregnancy that can affect both maternal and fetal
outcomes. Early-onset pre-eclampsia (EOPET) is a severe form of pre-eclampsia that is …
outcomes. Early-onset pre-eclampsia (EOPET) is a severe form of pre-eclampsia that is …
Purinergic transmission in blood vessels
V Ralevic, WR Dunn - Autonomic Neuroscience, 2015 - Elsevier
There are nineteen different receptor proteins for adenosine, adenine and uridine
nucleotides, and nucleotide sugars, belonging to three families of G protein-coupled …
nucleotides, and nucleotide sugars, belonging to three families of G protein-coupled …
Antagonism of adenosine A2A receptor expressed by lung adenocarcinoma tumor cells and cancer associated fibroblasts inhibits their growth
M Mediavilla-Varela, K Luddy, D Noyes… - Cancer biology & …, 2013 - Taylor & Francis
Recently it has become clear that the cost associated with the Warburg effect, which is
inefficient production of ATP, is offset by selective advantages that are produced by resultant …
inefficient production of ATP, is offset by selective advantages that are produced by resultant …
Akt/mTOR role in human foetoplacental vascular insulin resistance in diseases of pregnancy
R Villalobos-Labra, L Silva, M Subiabre… - Journal of Diabetes …, 2017 - Wiley Online Library
Insulin resistance is characteristic of pregnancies where the mother shows metabolic
alterations, such as preeclampsia (PE) and gestational diabetes mellitus (GDM), or …
alterations, such as preeclampsia (PE) and gestational diabetes mellitus (GDM), or …
[HTML][HTML] Gestational diabetes mellitus is associated with increased pro-migratory activation of vascular endothelial growth factor receptor 2 and reduced expression of …
F Troncoso, J Acurio, K Herlitz, C Aguayo, P Bertoglia… - PloS one, 2017 - journals.plos.org
Placentas from gestational diabetes mellitus (GDM) are often hypervascularized; however,
participation of vascular endothelial growth factor (VEGF) and its receptors in this placental …
participation of vascular endothelial growth factor (VEGF) and its receptors in this placental …
Adenosine and preeclampsia
Adenosine is an endogenous nucleoside with pleiotropic effects in different physiological
processes including circulation, renal blood flow, immune function, or glucose homeostasis …
processes including circulation, renal blood flow, immune function, or glucose homeostasis …
[HTML][HTML] Dietary adenosine supplementation improves placental angiogenesis in IUGR piglets by up-regulating adenosine A2a receptor
Z Wu, J Nie, D Wu, S Huang, J Chen, H Liang, X Hao… - Animal Nutrition, 2023 - Elsevier
Abnormal placental angiogenesis is associated with the occurrence of intrauterine growth
restriction (IUGR) in piglets, and effective treatment strategies against this occurrence …
restriction (IUGR) in piglets, and effective treatment strategies against this occurrence …
[HTML][HTML] Cerebral biomarkers and blood-brain barrier integrity in preeclampsia
T Friis, AK Wikström, J Acurio, J León, H Zetterberg… - Cells, 2022 - mdpi.com
Cerebral complications in preeclampsia contribute substantially to maternal mortality and
morbidity. There is a lack of reliable and accessible predictors for preeclampsia-related …
morbidity. There is a lack of reliable and accessible predictors for preeclampsia-related …