Despite advances in our understanding of the pathophysiology of many cardiovascular
diseases (CVDs) and expansion of available therapies, the global burden of CVD …

Nitric oxide (NO) is a key signalling molecule in the cardiovascular, immune and central
nervous systems, and crucial steps in the regulation of NO bioavailability in health and …

The human mouth harbours one of the most diverse microbiomes in the human body,
including viruses, fungi, protozoa, archaea and bacteria. The bacteria are responsible for the …

Gut microbiota is an assortment of microorganisms inhabiting the length and width of the
mammalian gastrointestinal tract. The composition of this microbial community is host …

The ability of ketogenic low‐carbohydrate (CHO) high‐fat (K‐LCHF) diets to enhance
muscle fat oxidation has led to claims that it is the 'future of elite endurance sport'. There is …

The discovery that dietary (inorganic) nitrate has important vascular effects came from the
relatively recent realization of the 'nitrate‐nitrite‐nitric oxide (NO) pathway'. Dietary nitrate …

Mitochondrially generated reactive oxygen species are involved in a myriad of signaling and
damaging pathways in different tissues. In addition, mitochondria are an important target of …

Inorganic nitrate and nitrite from endogenous or dietary sources are metabolized in vivo to
nitric oxide (NO) and other bioactive nitrogen oxides. The nitrate-nitrite-NO pathway is …

Nitrite is one of the players in the broad nitrogen biogeochemical cycle. This nitrogen oxo-
anion is involved in key pathways crucial to life on Earth and to the planetary “recycling” of …

The circulation of nitrogen in nature is a prerequisite for life on earth. In the nitrogen cycle
atmospheric nitrogen is fixated by bacteria into forms that can be utilized by plants and …