The microRNA in ventricular remodeling: the miR-30 family

X Zhang, S Dong, Q Jia, A Zhang, Y Li, Y Zhu… - Bioscience …, 2019 - portlandpress.com
Ventricular remodeling (VR) is a complex pathological process of cardiomyocyte apoptosis,
cardiac hypertrophy, and myocardial fibrosis, which is often caused by various …

Quantitative proteomic analyses reveal that GPX4 downregulation during myocardial infarction contributes to ferroptosis in cardiomyocytes

TJ Park, JH Park, GS Lee, JY Lee, JH Shin… - Cell death & …, 2019 - nature.com
Ischaemic heart disease (IHD) is the leading cause of death worldwide. Although myocardial
cell death plays a significant role in myocardial infarction (MI), its underlying mechanism …

The role of small extracellular vesicles in cerebral and myocardial ischemia—Molecular signals, treatment targets, and future clinical translation

X Zheng, DM Hermann, M Bähr, TR Doeppner - Stem Cells, 2021 - academic.oup.com
The heart and the brain mutually interact with each other, forming a functional axis that is
disturbed under conditions of ischemia. Stem cell-derived extracellular vesicles (EVs) show …

MicroRNA-30d-5p—A Potential New Therapeutic Target for Prevention of Ischemic Cardiomyopathy after Myocardial Infarction

E Boxhammer, V Paar, B Wernly, A Kiss, M Mirna… - Cells, 2023 - mdpi.com
(1) Background and Objective: MicroRNAs (miRs) are biomarkers for assessing the extent of
cardiac remodeling after myocardial infarction (MI) and important predictors of clinical …

Two sides of electrospun fiber in promoting and inhibiting biomedical processes

Z Wang, W Cui - Advanced Therapeutics, 2021 - Wiley Online Library
Electrospinning is a versatile technique for generating ultrathin fibers, which is widely
applied in various biomedical applications. The properties and structures of the fibers are …

[HTML][HTML] MicroRNA-30 regulates left ventricular hypertrophy in chronic kidney disease

J Bao, Y Lu, Q She, W Dou, R Tang, X Xu, M Zhang… - JCI insight, 2021 - ncbi.nlm.nih.gov
Left ventricular hypertrophy (LVH) is a primary feature of cardiovascular complications in
patients with chronic kidney disease (CKD). miRNA-30 is an important posttranscriptional …

ATAD3B and SKIL polymorphisms associated with antipsychotic-induced QTc interval change in patients with schizophrenia: a genome-wide association study

Z Lu, Y Zhang, H Yan, Y Su, L Guo, Y Liao, T Lu… - Translational …, 2022 - nature.com
QTc interval prolongation is one of the most common antipsychotic-induced side effects
which could lead to ventricular tachycardia or Torsade de Pointes, even cardiac arrest …

MicroRNAs—The Heart of Post-Myocardial Infarction Remodeling

L Maries, C Marian, R Sosdean, F Goanta, IO Sirbu… - Diagnostics, 2021 - mdpi.com
Myocardial infarction (MI) is one of the most frequent cardiac emergencies, with significant
potential for mortality. One of the major challenges of the post-MI healing response is that …

Fibulin-3 is necessary to prevent cardiac rupture following myocardial infarction

LA Murtha, SA Hardy, NS Mabotuwana, MJ Bigland… - Scientific reports, 2023 - nature.com
Despite the high prevalence of heart failure in the western world, there are few effective
treatments. Fibulin-3 is a protein involved in extracellular matrix (ECM) structural integrity …

Metabolomic analysis of the ameliorative effect of enhanced proline metabolism on hypoxia‐induced injury in cardiomyocytes

J Wang, Z Xue, C Hua, J Lin, Z Shen… - Oxidative Medicine …, 2020 - Wiley Online Library
Background. Coronary heart disease is currently the leading cause of death in humans. Its
poor prognosis and high mortality are associated with myocardial ischemia, which leads to …