Abstract Beta-2-Glycoprotein I (β2GPI) plays a number of essential roles throughout the
body. β2GPI, C-reactive protein and thrombomodulin are the only three proteins that …

The laboratory criteria that define patients with antiphospholipid syndrome (APS) include
lupus anticoagulant (LAC), anticardiolipin antibodies and anti‐β2 glycoprotein I antibodies …

Introduction Currently available clinical assays to detect antiphospholipid antibodies (aPL)
test for IgG and IgM antibodies to cardiolipin (aCL) and β2-glycoprotein I (aβ2GPI). It has …

Objective. IgG aPL against domain I of β 2-glycoprotein I (β 2 GPI)[anti-DI (aDI)] is
associated with the pathogenesis of APS, an autoimmune disease defined by thrombosis …

The clinical significance of IgG/IgM antiphosphatidylserine/prothrombin (aPS/PT) antibodies
was prospectively evaluated in a cohort of 191 antiphospholipid antibody (aPL) carriers …

The antiphospholipid (antibody) syndrome (APS) is an autoimmune condition characterised
by a wide range of clinical features, but primarily identified as thrombotic and/or obstetric …

Over 30 years since it was first described as a discrete clinical entity, the antiphospholipid
antibody syndrome (APS) remains a challenge for both laboratory workers and clinicians in …

During human pregnancy, the maternal immune system develops and changes, providing
protection for the growing placenta and fetus. These protective changes provide …

Introduction: Important advancements in pregnancy outcome have been reported in women
with antiphospholipid antibodies (aPL), despite the fact that the treatment of aPL related …

Background A major problem for diagnosing the antiphospholipid syndrome (APS) is the
high variability between commercial anti-β2glycoprotein I (β2GPI) assays. Predominantly …