Membrane lipids interact with proteins in a variety of ways, ranging from providing a stable
membrane environment for proteins to being embedded in to detailed roles in complicated …

Integrin receptors provide a dynamic, tightly-regulated link between the extracellular matrix
(or cellular counter-receptors) and intracellular cytoskeletal and signalling networks …

The bottom‐up construction of a synthetic cell from nonliving building blocks capable of
mimicking cellular properties and behaviors helps to understand the particular biophysical …

At least 468 individual genes have been manipulated by molecular methods to study their
effects on the initiation, promotion, and progression of atherosclerosis. Most clinicians and …

Filopodia are dynamic cell surface protrusions used for cell motility, pathogen infection, and
tissue development. The molecular mechanisms determining how and where filopodia grow …

Cancer cell invasion into healthy tissues develops preferentially along pre‐existing tracks of
least resistance, followed by secondary tissue remodelling and destruction. The tissue …

SARS-CoV-2 infection depends on binding its spike (S) protein to angiotensin-converting
enzyme 2 (ACE2). The S protein expresses an RGD motif, suggesting that integrins may be …

Significance: Regulation of cell adhesions during tissue repair is fundamentally important for
cell migration, proliferation, and protein production. All cells interact with extracellular matrix …

Talin activates integrins, couples them to F-actin, and recruits vinculin to focal adhesions
(FAs). Here, we report the structural characterization of the talin rod: 13 helical bundles (R1 …

The role of mechanical properties in cancer disease and inflammation is still
underinvestigated and even ignored in many oncological and immunological reviews. In …