The malignant tumor is a multi-etiological, systemic and complex disease characterized by
uncontrolled cell proliferation and distant metastasis. Anticancer treatments including …

Mesenchymal stem/stromal cells (MSCs) exist in almost all tissues and participate in tissue
regeneration and homeostasis. In-vitro-expanded MSCs are employed as therapeutics for …

An exceptional safety profile has been shown in a large number of cell therapy clinical trials
that use mesenchymal stromal cells (MSCs). However, reliable potency assays are still …

Myofibroblasts are the construction workers of wound healing and repair damaged tissues
by producing and organizing collagen/extracellular matrix (ECM) into scar tissue. Scar tissue …

The success of regenerative medicine in various clinical applications depends on the
appropriate selection of the source of mesenchymal stem cells (MSCs). Indeed, the source …

The term 'fibroblast'often serves as a catch-all for a diverse array of mesenchymal cells,
including perivascular cells, stromal progenitor cells and bona fide fibroblasts. Although …

Mesenchymal stem cells (MSCs) possess potent immunomodulatory activity and have been
extensively investigated for their therapeutic potential in treating inflammatory disorders …

Cardiovascular disease is the leading cause of death globally. An advanced understanding
of cardiovascular disease mechanisms is required to improve therapeutic strategies and …

Graft versus host disease (GvHD) is the clinical condition in which bone marrow-derived
mesenchymal stromal cells (MSCs) have been most frequently studied. In this review, we …

Fibroblasts differentiate into myofibroblasts by acquiring new contractile function. This is
important for tissue repair, but it also contributes to organ fibrosis. Platelet-derived growth …