Virtual clinical trials in medical imaging: a review

E Abadi, WP Segars, BMW Tsui… - Journal of Medical …, 2020 - spiedigitallibrary.org
The accelerating complexity and variety of medical imaging devices and methods have
outpaced the ability to evaluate and optimize their design and clinical use. This is a …

[HTML][HTML] The promise of AI in detection, diagnosis, and epidemiology for combating COVID-19: beyond the hype

M Abdulkareem, SE Petersen - Frontiers in Artificial Intelligence, 2021 - frontiersin.org
COVID-19 has created enormous suffering, affecting lives, and causing deaths. The ease
with which this type of coronavirus can spread has exposed weaknesses of many healthcare …

[HTML][HTML] Linking statistical shape models and simulated function in the healthy adult human heart

C Rodero, M Strocchi, M Marciniak… - PLoS computational …, 2021 - journals.plos.org
Cardiac anatomy plays a crucial role in determining cardiac function. However, there is a
poor understanding of how specific and localised anatomical changes affect different …

Pathophysiology of hypertensive heart disease: beyond left ventricular hypertrophy

CC Nwabuo, RS Vasan - Current hypertension reports, 2020 - Springer
Abstract Purpose of Review Given that the life expectancy and the burden of hypertension
are projected to increase over the next decade, hypertensive heart disease (HHD) may be …

[HTML][HTML] Multi-class point cloud completion networks for 3D cardiac anatomy reconstruction from cine magnetic resonance images

M Beetz, A Banerjee, J Ossenberg-Engels… - Medical Image Analysis, 2023 - Elsevier
Cine magnetic resonance imaging (MRI) is the current gold standard for the assessment of
cardiac anatomy and function. However, it typically only acquires a set of two-dimensional …

Association of longer leukocyte telomere length with cardiac size, function, and heart failure

N Aung, Q Wang, S van Duijvenboden, R Burns… - JAMA …, 2023 - jamanetwork.com
Importance Longer leukocyte telomere length (LTL) is associated with a lower risk of
adverse cardiovascular outcomes. The extent to which variation in LTL is associated with …

Cardiovascular magnetic resonance imaging in the UK Biobank: a major international health research resource

Z Raisi-Estabragh, NC Harvey… - European Heart …, 2021 - academic.oup.com
Abstract The UK Biobank (UKB) is a health research resource of major international
importance, incorporating comprehensive characterization of> 500 000 men and women …

[HTML][HTML] Multi-domain variational autoencoders for combined modeling of MRI-based biventricular anatomy and ECG-based cardiac electrophysiology

M Beetz, A Banerjee, V Grau - Frontiers in physiology, 2022 - frontiersin.org
Human cardiac function is characterized by a complex interplay of mechanical deformation
and electrophysiological conduction. Similar to the underlying cardiac anatomy, these …

Advanced imaging of right ventricular anatomy and function

LP Badano, K Addetia, G Pontone, C Torlasco… - Heart, 2020 - heart.bmj.com
Right ventricular (RV) size and function are important predictors of cardiovascular morbidity
and mortality in patients with various conditions. However, non-invasive assessment of the …

[HTML][HTML] Biventricular shape modes discriminate pulmonary valve replacement in tetralogy of Fallot better than imaging indices

S Govil, C Mauger, S Hegde, CJ Occleshaw, X Yu… - Scientific reports, 2023 - nature.com
Current indications for pulmonary valve replacement (PVR) in repaired tetralogy of Fallot
(rTOF) rely on cardiovascular magnetic resonance (CMR) image-based indices but are …