[HTML][HTML] On the design principles of peptide–drug conjugates for targeted drug delivery to the malignant tumor site
Cancer is the second leading cause of death affecting nearly one in two people, and the
appearance of new cases is projected to rise by> 70% by 2030. To effectively combat the …
appearance of new cases is projected to rise by> 70% by 2030. To effectively combat the …
[HTML][HTML] Natural peptides for immunological regulation in cancer therapy: mechanism, facts and perspectives
Y Zhang, C Liu, C Wu, L Song - Biomedicine & Pharmacotherapy, 2023 - Elsevier
Cancer incidence and mortality rates are increasing annually. Treatment with surgery,
chemotherapy and radiation therapy (RT) is unsatisfactory because many patients have …
chemotherapy and radiation therapy (RT) is unsatisfactory because many patients have …
[HTML][HTML] 3D approaches to model the tumor microenvironment of pancreatic cancer
In tumor engineering, 3D approaches are used to model components of the tumor
microenvironment and to test new treatments. Pancreatic cancers are a cancer of substantial …
microenvironment and to test new treatments. Pancreatic cancers are a cancer of substantial …
Pre-clinical models of metastasis in pancreatic cancer
M Miquel, S Zhang, C Pilarsky - Frontiers in cell and developmental …, 2021 - frontiersin.org
Pancreatic ductal adenocarcinoma (PDAC) is a hostile solid malignancy coupled with an
extremely high mortality rate. Metastatic disease is already found in most patients at the time …
extremely high mortality rate. Metastatic disease is already found in most patients at the time …
The interplay between neutrophils and microbiota in cancer
CK Smith, G Trinchieri - Journal of Leukocyte Biology, 2018 - academic.oup.com
The role of the microbiota in many diseases including cancer has gained increasing
attention. Paired with this is our expanding appreciation for the heterogeneity of the …
attention. Paired with this is our expanding appreciation for the heterogeneity of the …
Inoculation of Pan02 cells produces tumor nodules in mouse pancreas: Characterization of a novel orthotopic pancreatic ductal adenocarcinoma tumor model for …
Preclinical models of cancer are vital for assessing and predicting efficacies and toxicities of
novel treatments prior to testing in human subjects. Current pancreatic tumor models exhibit …
novel treatments prior to testing in human subjects. Current pancreatic tumor models exhibit …
Identification and validation of a hypoxia-immune related prognostic signature for pancreatic cancer
X Qinhong, M Fandi, W Yong, L Zhengyang, L Xuqi - 2022 - researchsquare.com
Pancreatic cancer remains a lethal disease with poor prognosis. Immune and hypoxia are
critical characteristics of tumor microenvironment, and are closely associated with cancer …
critical characteristics of tumor microenvironment, and are closely associated with cancer …
3D approaches to model the tumour microenvironment of pancreatic cancer
In tumor engineering, 3D approaches are used to model components of the tumor
microenvironment and to test new treatments. Pancreatic cancers are a cancer of substantial …
microenvironment and to test new treatments. Pancreatic cancers are a cancer of substantial …