Plant GSTome: structure and functional role in xenome network and plant stress response
Highlights•GSTome contributes to cell detoxification, metabolism, stress/signalling.•GSTome
is organized in evolutionary distinct supergene families and classes.•The structural flexibility …
is organized in evolutionary distinct supergene families and classes.•The structural flexibility …
Recent advances in protein engineering and biotechnological applications of glutathione transferases
F Perperopoulou, F Pouliou… - Critical reviews in …, 2018 - Taylor & Francis
Abstract Glutathione transferases (GSTs, EC 2.5. 1.18) are a widespread family of enzymes
that play a central role in the detoxification, metabolism, and transport or sequestration of …
that play a central role in the detoxification, metabolism, and transport or sequestration of …
Cytotoxic and genotoxic effects of abamectin, chlorfenapyr, and imidacloprid on CHOK1 cells
AS Al-Sarar, Y Abobakr, AE Bayoumi… - … Science and Pollution …, 2015 - Springer
The cytotoxicity and genotoxicity of abamectin, chlorfenapyr, and imidacloprid have been
evaluated on the Chinese hamster ovary (CHO K1) cells. Neutral red incorporation (NRI) …
evaluated on the Chinese hamster ovary (CHO K1) cells. Neutral red incorporation (NRI) …
Characterization and functional analysis of a recombinant tau class glutathione transferase GmGSTU2-2 from Glycine max
K Skopelitou, AW Muleta, AC Papageorgiou… - International journal of …, 2017 - Elsevier
The plant tau class glutathione transferases (GSTs) perform diverse catalytic as well as non-
catalytic roles in detoxification of xenobiotics, prevention of oxidative damage and …
catalytic roles in detoxification of xenobiotics, prevention of oxidative damage and …
An overview of biosensors based on glutathione transferases and for the detection of glutathione
Glutathione transferases are enzymes involved in the detoxification against xenobiotics and
noxious compounds. These enzymes catalyse a variety of reactions on many physiological …
noxious compounds. These enzymes catalyse a variety of reactions on many physiological …
Structure-based design and application of an engineered glutathione transferase for the development of an optical biosensor for pesticides determination
EG Chronopoulou, D Vlachakis… - … et Biophysica Acta (BBA …, 2019 - Elsevier
In the present work, a structure-based design approach was used for the generation of a
novel variant of synthetic glutathione transferase (PvGmGSTU) with higher sensitivity …
novel variant of synthetic glutathione transferase (PvGmGSTU) with higher sensitivity …
Directed evolution of glutathione transferases towards a selective glutathione-binding site and improved oxidative stability
I Axarli, AW Muleta, EG Chronopoulou… - … et Biophysica Acta (BBA …, 2017 - Elsevier
Abstract Background Glutathione transferases (GSTs) are a family of detoxification enzymes
that catalyze the conjugation of glutathione (GSH) to electrophilic compounds. Methods A …
that catalyze the conjugation of glutathione (GSH) to electrophilic compounds. Methods A …
Simple, selective and fast detection of acrylamide based on glutathione S-transferase
MP Bucur, B Bucur, GL Radu - RSC advances, 2018 - pubs.rsc.org
Acrylamide (AA) is a toxic compound formed in thermally prepared foods by Maillard
reaction. Besides foods, AA may be found in cosmetic products as an impurity of the widely …
reaction. Besides foods, AA may be found in cosmetic products as an impurity of the widely …
Expanding the plant GSTome through directed evolution: DNA shuffling for the generation of new synthetic enzymes with engineered catalytic and binding properties
EG Chronopoulou, AC Papageorgiou, F Ataya… - Frontiers in Plant …, 2018 - frontiersin.org
Glutathione transferases (GSTs, EC. 2.5. 1.18) are inducible multifunctional enzymes that
are essential in the detoxification and degradation of toxic compounds. GSTs have …
are essential in the detoxification and degradation of toxic compounds. GSTs have …
A Key Role in Catalysis and Enzyme Thermostability of a Conserved Helix H5 Motif of Human Glutathione Transferase A1-1
EG Chronopoulou, L Mutabdzija, N Poudel… - International journal of …, 2023 - mdpi.com
Glutathione transferases (GSTs) are promiscuous enzymes whose main function is the
detoxification of electrophilic compounds. These enzymes are characterized by structural …
detoxification of electrophilic compounds. These enzymes are characterized by structural …