Accessing p‐Hydroxycinnamic Acids: Chemical Synthesis, Biomass Recovery, or Engineered Microbial Production?
AL Flourat, J Combes, C Bailly‐Maitre‐Grand… - …, 2021 - Wiley Online Library
Abstract p‐Hydroxycinnamic acids (ie, p‐coumaric, ferulic, sinapic, and caffeic acids) are
phenolic compounds involved in the biosynthesis pathway of lignin. These naturally …
phenolic compounds involved in the biosynthesis pathway of lignin. These naturally …
Biological valorization of lignin to flavonoids
Lignin is the most affluent natural aromatic biopolymer on the earth, which is the promising
renewable source for valuable products to promote the sustainability of biorefinery …
renewable source for valuable products to promote the sustainability of biorefinery …
[HTML][HTML] De novo biosynthesis of bioactive isoflavonoids by engineered yeast cell factories
Isoflavonoids comprise a class of plant natural products with great nutraceutical,
pharmaceutical and agricultural significance. Their low abundance in nature and structural …
pharmaceutical and agricultural significance. Their low abundance in nature and structural …
Remodelling metabolism for high-level resveratrol production in Yarrowia lipolytica
M Liu, C Wang, X Ren, S Gao, S Yu, J Zhou - Bioresource Technology, 2022 - Elsevier
Resveratrol is a polyphenol with numerous applications in food, pharma, and cosmetics.
Lack of precursors and low titer are the main problems hindering industrial scale resveratrol …
Lack of precursors and low titer are the main problems hindering industrial scale resveratrol …
Construction of an l-Tyrosine Chassis in Pichia pastoris Enhances Aromatic Secondary Metabolite Production from Glycerol
R Kumokita, T Bamba, K Inokuma, T Yoshida… - ACS Synthetic …, 2022 - ACS Publications
Bioactive plant-based secondary metabolites such as stilbenoids, flavonoids, and
benzylisoquinoline alkaloids (BIAs) are produced from l-tyrosine (l-Tyr) and have a wide …
benzylisoquinoline alkaloids (BIAs) are produced from l-tyrosine (l-Tyr) and have a wide …
Towards the sustainable production of bulk-chemicals using biotechnology
JM Woodley - New biotechnology, 2020 - Elsevier
The design and development of new routes for the production of sustainable bulk-chemicals
requires focus on feedstock, conversion technology and downstream product recovery. This …
requires focus on feedstock, conversion technology and downstream product recovery. This …
[HTML][HTML] Synthetic biology-driven microbial production of resveratrol: advances and perspectives
C Feng, J Chen, W Ye, K Liao, Z Wang… - … in Bioengineering and …, 2022 - frontiersin.org
Resveratrol, a bioactive natural product found in many plants, is a secondary metabolite and
has attracted much attention in the medicine and health care products fields due to its …
has attracted much attention in the medicine and health care products fields due to its …
[HTML][HTML] Metabolic engineering of Rhodotorula toruloides for resveratrol production
M Zhang, Q Gao, Y Liu, Z Fang, Z Gong, ZK Zhao… - Microbial Cell …, 2022 - Springer
Background Resveratrol is a plant-derived phenylpropanoid with diverse biological activities
and pharmacological applications. Plant-based extraction could not satisfy ever-increasing …
and pharmacological applications. Plant-based extraction could not satisfy ever-increasing …
[HTML][HTML] Engineering yeast mitochondrial metabolism for 3-hydroxypropionate production
Background With unique physiochemical environments in subcellular organelles, there has
been growing interest in harnessing yeast organelles for bioproduct synthesis. Among these …
been growing interest in harnessing yeast organelles for bioproduct synthesis. Among these …
[HTML][HTML] Rational engineering of Kluyveromyces marxianus to create a chassis for the production of aromatic products
AS Rajkumar, JP Morrissey - Microbial Cell Factories, 2020 - Springer
Abstract Background The yeast Kluyveromyces marxianus offers unique potential for
industrial biotechnology because of useful features like rapid growth, thermotolerance and a …
industrial biotechnology because of useful features like rapid growth, thermotolerance and a …