Effective regulation of immune-cell activation is critical for ensuring that the immune
response, and inflammation generated for the purpose of pathogen elimination, are limited …

Epithelial‐to‐mesenchymal transition (EMT) is the first step in the development of the
invasive and migratory properties of cancer metastasis. Since the transcriptional …

Mechanical cues from the extracellular matrix (ECM) regulate various cellular processes via
distinct mechanotransduction pathways. In breast cancer, increased ECM stiffness promotes …

Altered intestinal microbial composition promotes intestinal barrier dysfunction and triggers
the initiation and recurrence of inflammatory bowel disease (IBD). Current treatments for IBD …

Epigenetic plasticity is a pivotal factor that drives metastasis. Here, we show that the
promoter of the gene that encodes the ubiquitin ligase subunit FBXL7 is hypermethylated in …

The World Health Organisation reported COPD to be the third leading cause of death
globally in 2019, and in 2020, the most common cause of cancer death was lung cancer; …

Colorectal cancer (CRC) is one of the most common malignancies worldwide. Metastasis is
a major cause of CRC recurrence and mortality. Several antibiotic drugs have been reported …

Gastrointestinal adenocarcinomas (GIAC) of the tubular gastrointestinal (GI) tract including
esophagus, stomach, colon, and rectum comprise most GI cancers and share a spectrum of …

Gastric cancer (GC) is one of malignant tumors with high mortality and morbidity in the world.
MicroRNA-122 (miR-122) acts as a tumor suppressor in a variety of cancers and has been …

FBXO28 is a member of F-box proteins that are the substrate receptors of SCF (SKP1,
CULLIN1, F-box protein) ubiquitin ligase complexes. Despite the implications of its role in …