[HTML][HTML] The secretion profile of mesenchymal stem cells and potential applications in treating human diseases

Y Han, J Yang, J Fang, Y Zhou, E Candi… - … and Targeted Therapy, 2022 - nature.com
Mesenchymal stromal/stem cells (MSCs) possess multi-lineage differentiation and self-
renewal potentials. MSCs-based therapies have been widely utilized for the treatment of …

[HTML][HTML] Chemokines modulate immune surveillance in tumorigenesis, metastasis, and response to immunotherapy

AE Vilgelm, A Richmond - Frontiers in immunology, 2019 - frontiersin.org
Chemokines are small secreted proteins that orchestrate migration and positioning of
immune cells within the tissues. Chemokines are essential for the function of the immune …

Mesenchymal stem cell therapy for the treatment of inflammatory diseases: challenges, opportunities, and future perspectives

S Regmi, S Pathak, JO Kim, CS Yong… - European journal of cell …, 2019 - Elsevier
Mesenchymal stem cells (MSCs) are promising alternative agents for the treatment of
inflammatory disorders due to their immunomodulatory functions, and several clinical trials …

[HTML][HTML] The impact of gut microbiota on radiation-induced enteritis

Y Jian, D Zhang, M Liu, Y Wang, ZX Xu - Frontiers in cellular and …, 2021 - frontiersin.org
Radiotherapy is an important treatment for abdominal tumors. A critical side effect for this
therapy is enteritis. In this review, we aim to summarize recent findings in radiation enteritis …

[HTML][HTML] Mesenchymal stem cell therapy: hope for patients with systemic lupus erythematosus

A Li, F Guo, Q Pan, S Chen, J Chen, H Liu… - Frontiers in …, 2021 - frontiersin.org
Systemic lupus erythematosus (SLE) is a chronic autoimmune disease. Although previous
studies have demonstrated that SLE is related to the imbalance of cells in the immune …

Bioactive factors for cartilage repair and regeneration: improving delivery, retention, and activity

JM Patel, KS Saleh, JA Burdick, RL Mauck - Acta Biomaterialia, 2019 - Elsevier
Articular cartilage is a remarkable tissue whose sophisticated composition and architecture
allow it to withstand complex stresses within the joint. Once injured, cartilage lacks the …

[HTML][HTML] Genetic engineering as a strategy to improve the therapeutic efficacy of mesenchymal stem/stromal cells in regenerative medicine

PKF Damasceno, TSA De Santana… - Frontiers in Cell and …, 2020 - frontiersin.org
Mesenchymal stem/stromal cells (MSCs) have been widely studied in the field of
regenerative medicine for applications in the treatment of several disease settings. The …

CCR2-engineered mesenchymal stromal cells accelerate diabetic wound healing by restoring immunological homeostasis

S Kuang, F He, G Liu, X Sun, J Dai, A Chi, Y Tang, Z Li… - Biomaterials, 2021 - Elsevier
Impaired wound healing presents great health risks to patients. While encouraging, the
current clinical successes of mesenchymal stromal cell (MSC)-based therapies for tissue …

[HTML][HTML] Oxidative stress and chemoradiation-induced oral mucositis: a scoping review of in vitro, in vivo and clinical studies

H Nguyen, S Sangha, M Pan, DH Shin, H Park… - International Journal of …, 2022 - mdpi.com
Chemoradiation-induced mucositis is a debilitating condition of the gastrointestinal tract
eventuating from antineoplastic treatment. It is believed to occur primarily due to oxidative …

Mesenchymal stem cells overexpressing heme oxygenase‐1 ameliorate lipopolysaccharide‐induced acute lung injury in rats

X Chen, S Wu, L Tang, L Ma, F Wang… - Journal of Cellular …, 2019 - Wiley Online Library
Acute lung injury (ALI) and acute respiratory distress syndrome (ARDS) are common and
potentially lethal clinical syndromes characterized by acute respiratory failure resulting from …