Retinopathy of prematurity

O Dammann, ME Hartnett… - Developmental Medicine & …, 2023 - Wiley Online Library
Retinopathy of prematurity (ROP) is a devastating neurovascular disease of the retina in
newborn infants that can lead to vision deficits or even blindness. In this concise review we …

Ischemic retinopathies: oxidative stress and inflammation

JC Rivera, R Dabouz, B Noueihed… - Oxidative medicine …, 2017 - Wiley Online Library
Ischemic retinopathies (IRs), such as retinopathy of prematurity (ROP), diabetic retinopathy
(DR), and (in many cases) age‐related macular degeneration (AMD), are ocular disorders …

Neonatal sepsis as a cause of retinopathy of prematurity: An etiological explanation

O Dammann, BK Stansfield - Progress in Retinal and Eye Research, 2024 - Elsevier
Retinopathy of prematurity (ROP) is a complex neonatal disorder with multiple contributing
factors. In this paper we have mounted the evidence in support of the proposal that neonatal …

Ocular vascular diseases: from retinal immune privilege to inflammation

X Wang, T Wang, E Lam, D Alvarez, Y Sun - International Journal of …, 2023 - mdpi.com
The eye is an immune privileged tissue that insulates the visual system from local and
systemic immune provocation to preserve homeostatic functions of highly specialized retinal …

Choroidal thickness and ocular growth in childhood

E Prousali, A Dastiridou, N Ziakas, S Androudi… - Survey of …, 2021 - Elsevier
The involvement of the choroid in ocular growth regulation has been postulated in studies
showing that refractive errors correlate with alterations in choroidal thickness (ChT). The …

[HTML][HTML] TNF‐α signaling regulates RUNX1 function in endothelial cells

HAB Whitmore, D Amarnani, M O'Hare… - The FASEB …, 2021 - ncbi.nlm.nih.gov
Runt‐related transcription factor 1 (RUNX1) acts as a mediator of aberrant retinal
angiogenesis and has been implicated in the progression of proliferative diabetic …

The ambiguous aspects of oxygen

G Napolitano, G Fasciolo, P Venditti - Oxygen, 2022 - mdpi.com
For most living beings, oxygen is an essential molecule for survival, being the basis of
biological oxidations, which satisfy most of the energy needs of aerobic organisms. Oxygen …

Microglial extracellular vesicles as vehicles for neurodegeneration spreading

ID Aires, T Ribeiro-Rodrigues, R Boia… - Biomolecules, 2021 - mdpi.com
Microglial cells are the neuroimmune competent cells of the central nervous system. In the
adult, microglia are responsible for screening the neuronal parenchyma searching for …

Small-medium extracellular vesicles and their miRNA cargo in retinal health and degeneration: mediators of homeostasis, and vehicles for targeted gene therapy

Y Wooff, AV Cioanca, JA Chu-Tan… - Frontiers in Cellular …, 2020 - frontiersin.org
Photoreceptor cell death and inflammation are known to occur progressively in retinal
degenerative diseases such as age-related macular degeneration (AMD). However, the …

Early and late onset sepsis and retinopathy of prematurity in a cohort of preterm infants

E Bonafiglia, E Gusson, R Longo, B Ficial, MG Tisato… - Scientific Reports, 2022 - nature.com
This study investigates the impact of antenatal and postnatal infection or inflammation on the
onset and progression of Retinopathy of Prematurity (ROP). We retrospectively collected …