Recent advances in microfluidic technology for bioanalysis and diagnostics

SF Berlanda, M Breitfeld, CL Dietsche… - Analytical …, 2020 - ACS Publications
Microfluidics has become a mature technology, providing an excellent toolbox for the
handling and manipulation of fluid samples, suspended cells, and particles. About 30 years …

Droplet microfluidics for CTC-based liquid biopsy: a review

L Jiang, H Yang, W Cheng, Z Ni, N Xiang - Analyst, 2023 - pubs.rsc.org
Circulating tumor cells (CTCs) are important biomarkers of liquid biopsy. The number and
heterogeneity of CTCs play an important role in cancer diagnosis and personalized …

Methodologies, technologies, and strategies for acoustic streaming-based acoustofluidics

M Stringer, Z Zeng, X Zhang, Y Chai, W Li… - Applied Physics …, 2023 - pubs.aip.org
Acoustofluidics offers contact-free manipulation of particles and fluids, enabling their uses in
various life sciences, such as for biological and medical applications. Recently, there have …

Acoustofluidic black holes for multifunctional in-droplet particle manipulation

P Liu, Z Tian, K Yang, TD Naquin, N Hao, H Huang… - Science …, 2022 - science.org
Acoustic black holes offer superior capabilities for slowing down and trapping acoustic
waves for various applications such as metastructures, energy harvesting, and vibration and …

Acoustofluidic separation enables early diagnosis of traumatic brain injury based on circulating exosomes

Z Wang, H Wang, R Becker, J Rufo, S Yang… - Microsystems & …, 2021 - nature.com
Traumatic brain injury (TBI) is a global cause of morbidity and mortality. Initial management
and risk stratification of patients with TBI is made difficult by the relative insensitivity of …

Active single cell encapsulation using SAW overcoming the limitations of Poisson distribution

A Link, JS McGrath, M Zaimagaoglu, T Franke - Lab on a Chip, 2022 - pubs.rsc.org
We demonstrate the use of an acoustic device to actively encapsulate single red blood cells
into individual droplets in a T-junction. We compare the active encapsulation with the …

A Comprehensive Review of Surface Acoustic Wave-Enabled Acoustic Droplet Ejection Technology and Its Applications

J Ning, Y Lei, H Hu, C Gai - Micromachines, 2023 - mdpi.com
This review focuses on the development of surface acoustic wave-enabled acoustic drop
ejection (SAW-ADE) technology, which utilizes surface acoustic waves to eject droplets from …

Numerical study of thermocapillary and slip effects on interfacial destabilization under surface acoustic waves

J Ning, QY Huang, CH Gai, YZ Ding, B Zhang… - Physics of …, 2024 - pubs.aip.org
The rapid development of microfluidics has significantly highlighted the role of surface
acoustic waves (SAWs) in microfluidic actuation. SAW influences droplet manipulation …

Coalescence of droplets in a microwell driven by surface acoustic waves

A Sudeepthi, A Nath, LY Yeo, AK Sen - Langmuir, 2021 - ACS Publications
Microwell arrays are amongst the most commonly used platforms for biochemical assays.
However, the coalescence of droplets that constitute the dispersed phase of suspensions …

Trapping of aqueous droplets under surface acoustic wave-driven streaming in oil-filled microwells

A Nath, A Sudeepthi, AK Sen - Langmuir, 2022 - ACS Publications
Microwell arrays are ideal platforms for cell culturing, cell separation, and low-volume liquid
handling. The ability to manipulate droplets in microwells could open up the opportunity for …