[HTML][HTML] Epigenetics of male infertility: the role of DNA methylation

JC Rotondo, C Lanzillotti, C Mazziotta… - Frontiers in Cell and …, 2021 - frontiersin.org
In recent years, a number of studies focused on the role of epigenetics, including DNA
methylation, in spermatogenesis and male infertility. We aimed to provide an overview of the …

SARS-CoV-2 infection: new molecular, phylogenetic, and pathogenetic insights. Efficacy of current vaccines and the potential risk of variants

JC Rotondo, F Martini, M Maritati, C Mazziotta… - Viruses, 2021 - mdpi.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a newly discovered
coronavirus responsible for the coronavirus disease 2019 (COVID-19) pandemic. COVID-19 …

Advanced molecular and immunological diagnostic methods to detect SARS-CoV-2 infection

JC Rotondo, F Martini, M Maritati, E Caselli… - Microorganisms, 2022 - mdpi.com
Simple Summary COVID-19 emerged in late 2019 in China and rapidly spread across the
globe. After 2 years, numerous advances have been made. First of all, the preventive …

Cancer biology and molecular genetics of A3 adenosine receptor

C Mazziotta, JC Rotondo, C Lanzillotti, G Campione… - Oncogene, 2022 - nature.com
Abstract A3 adenosine receptor (A3AR) is a cell membrane protein, which has been found to
be overexpressed in a large number of cancer types. This receptor plays an important role in …

The role of purinergic P2X7 receptor in inflammation and cancer: novel molecular insights and clinical applications

JC Rotondo, C Mazziotta, C Lanzillotti, C Stefani… - Cancers, 2022 - mdpi.com
Simple Summary The purinergic P2X7 receptor (P2X7R) is a cell membrane protein whose
activation has been related to a variety of cellular processes, while its dysregulation has …

[HTML][HTML] Simultaneous detection and viral DNA load quantification of different human papillomavirus types in clinical specimens by the high analytical droplet digital …

JC Rotondo, L Oton-Gonzalez, C Mazziotta… - Frontiers in …, 2020 - frontiersin.org
Human papillomaviruses (HPVs) are small DNA tumor viruses that mainly infect mucosal
epithelia of anogenital and upper respiratory tracts. There has been progressive demand for …

[HTML][HTML] Significantly low levels of IgG antibodies against oncogenic Merkel cell polyomavirus in sera from females affected by spontaneous abortion

C Mazziotta, G Pellielo, M Tognon, F Martini… - Frontiers in …, 2021 - frontiersin.org
Merkel cell polyomavirus (MCPyV) is a small DNA tumor virus ubiquitous in humans. MCPyV
establishes a clinically asymptomatic lifelong infection in healthy immunocompetent …

Investigation on spontaneous abortion and human papillomavirus infection

M Tognon, A Tagliapietra, F Magagnoli, C Mazziotta… - Vaccines, 2020 - mdpi.com
Viral infections are considered to be risk factors for spontaneous abortion (SA). Conflicting
results have been reported on the association between Human Papillomavirus (HPV) and …

Designing a Multi-Epitope Vaccine against Chlamydia trachomatis by Employing Integrated Core Proteomics, Immuno-Informatics and In Silico Approaches

S Aslam, S Ahmad, F Noor, UA Ashfaq, F Shahid… - Biology, 2021 - mdpi.com
Simple Summary Chlamydia trachomatis is the most common cause of blindness, ectopic
pregnancy, and bacterial sexually transmitted infections. These diseases affect mostly young …

Mycoplasma genitalium infection in the female reproductive system: Diseases and treatment

J Yu, Y Zhou, H Luo, X Su, T Gan, J Wang… - Frontiers in …, 2023 - frontiersin.org
Mycoplasma genitalium is a newly emerged sexually transmitted disease pathogen and an
independent risk factor for female cervicitis and pelvic inflammatory disease. The clinical …