The glycome describes the complete repertoire of glycoconjugates composed of
carbohydrate chains, or glycans, that are covalently linked to lipid or protein molecules …

Proteomic analysis of cells, tissues and body fluids has generated valuable insights into the
complex processes influencing human biology. Proteins represent intermediate phenotypes …

Intestinal mucus forms the first line of defense against bacterial invasion while providing
nutrition to support microbial symbiosis. How the host controls mucus barrier integrity and …

Inflammatory bowel disease (IBD) affects 6.8 million people globally. A variety of factors
have been implicated in IBD pathogenesis, including host genetics, immune dysregulation …

IgA mediates microbial homeostasis at the intestinal mucosa. Within the gut, IgA acts in a
context-dependent manner to both prevent and promote bacterial colonization and to …

The availability of host and dietary carbohydrates in the gastrointestinal (GI) tract plays a key
role in shaping the structure-function of the microbiota. In particular, some gut bacteria have …

Akkermansia muciniphila utilises colonic mucin as its substrate. Abundance is reduced in
ulcerative colitis (UC), as is the relative proportion of sulphated mucin in the mucus gel layer …

This study was designed to explore the effects and discrepancy of different CLA-producing
Bifidobacterium pseudocatenulatum on relieving colitis and to investigate the potential …

Reactive oxygen species (ROS), initially categorized as toxic by-products of aerobic
metabolism, have often been called a double-edged sword. ROS are considered …

ABSTRACT A close symbiotic relationship exists between the intestinal microbiota and its
host. A critical component of gut homeostasis is the presence of a mucus layer covering the …