[HTML][HTML] Molecular targets of manganese-induced neurotoxicity: A five-year update
AA Tinkov, MMB Paoliello, AN Mazilina… - International journal of …, 2021 - mdpi.com
Understanding of the immediate mechanisms of Mn-induced neurotoxicity is rapidly
evolving. We seek to provide a summary of recent findings in the field, with an emphasis to …
evolving. We seek to provide a summary of recent findings in the field, with an emphasis to …
Influence of iron metabolism on manganese transport and toxicity
Q Ye, JE Park, K Gugnani, S Betharia… - Metallomics, 2017 - academic.oup.com
Although manganese (Mn) is critical for the proper functioning of various metabolic enzymes
and cofactors, excess Mn in the brain causes neurotoxicity. While the exact transport …
and cofactors, excess Mn in the brain causes neurotoxicity. While the exact transport …
Neurotoxic effects of heavy metal pollutants in the environment: Focusing on epigenetic mechanisms
G Yu, L Wu, Q Su, X Ji, J Zhou, S Wu, Y Tang… - Environmental Pollution, 2024 - Elsevier
The pollution of heavy metals (HMs) in the environment is a significant global environmental
issue, characterized by its extensive distribution, severe contamination, and profound …
issue, characterized by its extensive distribution, severe contamination, and profound …
[HTML][HTML] Endocrine disruptors also function as nervous disruptors and can be renamed endocrine and nervous disruptors (ENDs)
GE Seralini, G Jungers - Toxicology reports, 2021 - Elsevier
Endocrine disruption (ED) and endocrine disruptors (EDs) emerged as scientific concepts in
1995, after numerous chemical pollutants were found to be responsible for reproductive …
1995, after numerous chemical pollutants were found to be responsible for reproductive …
[HTML][HTML] Manganese chloride (MnCl2) induced novel model of Parkinson's disease in adult Zebrafish; Involvement of oxidative stress, neuroinflammation and …
APR Nadig, B Huwaimel, A Alobaida… - Biomedicine & …, 2022 - Elsevier
Parkinson's disease (PD) is a progressive neurodegenerative disorder imposing a severe
health and socioeconomic burden worldwide. Existing pharmacological approaches for …
health and socioeconomic burden worldwide. Existing pharmacological approaches for …
[HTML][HTML] Mechanisms of manganese-induced neurotoxicity and the pursuit of neurotherapeutic strategies
E Pajarillo, I Nyarko-Danquah, A Digman… - Frontiers in …, 2022 - frontiersin.org
Chronic exposure to elevated levels of manganese via occupational or environmental
settings causes a neurological disorder known as manganism, resembling the symptoms of …
settings causes a neurological disorder known as manganism, resembling the symptoms of …
[HTML][HTML] Impact of environmental risk factors on mitochondrial dysfunction, neuroinflammation, protein misfolding, and oxidative stress in the etiopathogenesis of …
As a prevalent progressive neurodegenerative disorder, Parkinson's disease (PD) is
characterized by the neuropathological hallmark of the loss of nigrostriatal dopaminergic …
characterized by the neuropathological hallmark of the loss of nigrostriatal dopaminergic …
[HTML][HTML] Outlining potential biomarkers of exposure and effect to critical minerals: Nutritionally essential trace elements and the rare earth elements
JA Jenkins, ML Musgrove, SJO White - Toxics, 2023 - mdpi.com
Emerging and low-carbon technologies and innovations are driving a need for domestic
sources, sustainable use, and availability of critical minerals (CMs)—those vital to the …
sources, sustainable use, and availability of critical minerals (CMs)—those vital to the …
Differential DNA methylation in newborns with maternal exposure to heavy metals from an e-waste recycling area
Z Zeng, X Huo, Y Zhang, MN Hylkema, Y Wu… - Environmental research, 2019 - Elsevier
This study explored the effects of maternal exposure to e-waste environmental heavy metals
on neonatal DNA methylation patterns. Neonatal umbilical cord blood (UCB) samples were …
on neonatal DNA methylation patterns. Neonatal umbilical cord blood (UCB) samples were …
d-Ribose-l-Cysteine Improves Glutathione Levels, Neuronal and Mitochondrial Ultrastructural Damage, Caspase-3 and GFAP Expressions Following Manganese …
Repeated manganese (Mn) exposure may cause increased production of reactive oxygen
species (ROS), with a consequent imbalance in the glutathione (GSH) antioxidant defence …
species (ROS), with a consequent imbalance in the glutathione (GSH) antioxidant defence …