Angiogenesis after acute myocardial infarction

X Wu, MR Reboll, M Korf-Klingebiel… - Cardiovascular …, 2021 - academic.oup.com
Acute myocardial infarction (MI) inflicts massive injury to the coronary microcirculation
leading to vascular disintegration and capillary rarefication in the infarct region. Tissue …

Physiology and pharmacology of DPP-4 in glucose homeostasis and the treatment of type 2 diabetes

CF Deacon - Frontiers in endocrinology, 2019 - frontiersin.org
Dipeptidyl peptidase-4 (DPP-4), also known as the T-cell antigen CD26, is a multi-functional
protein which, besides its catalytic activity, also functions as a binding protein and a ligand …

Pharmacology, physiology, and mechanisms of action of dipeptidyl peptidase-4 inhibitors

EE Mulvihill, DJ Drucker - Endocrine reviews, 2014 - academic.oup.com
Abstract Dipeptidyl peptidase-4 (DPP4) is a widely expressed enzyme transducing actions
through an anchored transmembrane molecule and a soluble circulating protein. Both …

DPP4 in diabetes

D Röhrborn, N Wronkowitz, J Eckel - Frontiers in immunology, 2015 - frontiersin.org
Dipeptidyl-peptidase 4 (DPP4) is a glycoprotein of 110 kDa, which is ubiquitously expressed
on the surface of a variety of cells. This exopeptidase selectively cleaves N-terminal …

Pericardial Delivery of SDF‐1α Puerarin Hydrogel Promotes Heart Repair and Electrical Coupling

L Luo, Y Li, Z Bao, D Zhu, G Chen, W Li… - Advanced …, 2024 - Wiley Online Library
The stromal‐derived factor 1α/chemokine receptor 4 (SDF‐1α/CXCR4) axis contributes to
myocardial protection after myocardial infarction (MI) by recruiting endogenous stem cells …

[HTML][HTML] Endothelial dysfunction in diabetes: the role of reparatory mechanisms

A Avogaro, M Albiero, L Menegazzo… - Diabetes …, 2011 - ncbi.nlm.nih.gov
Type 2 diabetes is characterized by a two-to fourfold increased risk of cardiovascular
disease. This is generally attributed to the adverse effects of hyperglycemia and oxidative …

Cardiovascular biology of the incretin system

JR Ussher, DJ Drucker - Endocrine reviews, 2012 - academic.oup.com
Glucagon-like peptide-1 (GLP-1) is an incretin hormone that enhances glucose-stimulated
insulin secretion and exerts direct and indirect actions on the cardiovascular system. GLP-1 …

Cardiovascular actions of incretin-based therapies

JR Ussher, DJ Drucker - Circulation research, 2014 - Am Heart Assoc
Glucagon-like peptide-1 receptor (GLP-1R) agonists and dipeptidyl peptidase-4 (DPP-4)
inhibitors represent 2 distinct classes of incretin-based therapies used for the treatment of …

Homing of endogenous stem/progenitor cells for in situ tissue regeneration: promises, strategies, and translational perspectives

FM Chen, LA Wu, M Zhang, R Zhang, HH Sun - Biomaterials, 2011 - Elsevier
Stem cell-based therapy has been one of the best documented approaches in regenerative
medicine, promising cures for a multitude of diseases and disorders. However, the ex vivo …

In situ tissue regeneration through host stem cell recruitment

IK Ko, SJ Lee, A Atala, JJ Yoo - Experimental & molecular medicine, 2013 - nature.com
The field of tissue engineering has made steady progress in translating various tissue
applications. Although the classical tissue engineering strategy, which involves the use of …