Background: Thiazole is a good pharmacophore nucleus due to its various pharmaceutical
applications. Its derivatives have a wide range of biological activities such as antioxidant …

In recent years their has been an increased use of antifungal agents and has resulted in the
development of resistance to drugs. Currently, use of standard antifungal therapies can be …

Triazole compounds containing three nitrogen atoms in the five-membered aromatic azole
ring are readily able to bind with a variety of enzymes and receptors in biological system via …

Azole compounds are an important class of nitrogen heterocycles with electron-rich
property. This special structure endows azole-based derivatives easily bind with the …

Discovered in late 1960, azoles are heterocyclic compounds class which constitute the
largest group of available antifungal drugs. Particularly, the imidazole ring is the chemical …

Chemotherapy is widely used for cancer treatment. However, many chemotherapeutic drugs
are insoluble in water, and many show similar toxicities toward target cells and healthy cells …

Herein we report on our studies on the sequential one‐pot combinations of amine‐catalyzed
multicomponent reactions (MCRs). We have developed the copper‐free synthesis of …

In recent years, heterocyclic compounds, analogs, and derivatives have attracted strong
interest due to their useful biological and pharmacological properties. The small and simple …

A series of novel amine-derived bis-azole compounds were designed by the systematical
structural modification of Fluconazole and synthesized by a convenient and efficient method …

Positively charged halloysite nanotubes functionalized with triazolium salts (f-HNT) were
employed as a carrier for curcumin molecules delivery. The synthesis of these f-HNT new …