Classical and noncanonical functions of miRNAs in cancers
Alterations in microRNAs (miRNAs) expression are causative in the initiation and
progression of human cancers. The molecular events responsible for the widespread …
progression of human cancers. The molecular events responsible for the widespread …
Regulatory mechanisms of epigenetic miRNA relationships in human cancer and potential as therapeutic targets
Simple Summary By the virtue of targeting multiple genes, a microRNA (miRNA) can infer
variable consequences on tumorigenesis by appearing as both a tumour suppressor and …
variable consequences on tumorigenesis by appearing as both a tumour suppressor and …
miRNet-dissecting miRNA-target interactions and functional associations through network-based visual analysis
Y Fan, K Siklenka, SK Arora, P Ribeiro… - Nucleic acids …, 2016 - academic.oup.com
MicroRNAs (miRNAs) can regulate nearly all biological processes and their dysregulation is
implicated in various complex diseases and pathological conditions. Recent years have …
implicated in various complex diseases and pathological conditions. Recent years have …
MicroRNA regulatory network analysis using miRNet 2.0
MicroRNAs exert their effects in the context of gene regulatory networks. The recent
development of high-throughput experimental approaches and the growing availability of …
development of high-throughput experimental approaches and the growing availability of …
miRNet—functional analysis and visual exploration of miRNA–target interactions in a network context
To gain functional insights into microRNAs (miRNAs), researchers usually look for pathways
or biological processes that are overrepresented in their target genes. The interpretation is …
or biological processes that are overrepresented in their target genes. The interpretation is …
MicroRNAs: new players in IBD
MicroRNAs (miRNAs) are small non-coding RNAs, 18–23 nucleotides long, which act as
post-transcriptional regulators of gene expression. miRNAs are strongly implicated in the …
post-transcriptional regulators of gene expression. miRNAs are strongly implicated in the …
Ecotoxic pharmaceuticals, personal care products, and other emerging contaminants: A review of environmental, receptor-mediated, developmental, and epigenetic …
Pharmaceuticals and personal care products (PPCPs), other emerging contaminants (ECs),
and metabolites thereof are ubiquitous in the environment, both built and natural. While such …
and metabolites thereof are ubiquitous in the environment, both built and natural. While such …
Epigenetic regulation mechanisms of microRNA expression
MicroRNAs (miRNAs) are single-stranded RNAs of 18–25 nucleotides that regulate gene
expression at the post-transcriptional level. They are involved in many physiological and …
expression at the post-transcriptional level. They are involved in many physiological and …
Epi-drugs and Epi-miRs: moving beyond current cancer therapies
R Salarinia, A Sahebkar, M Peyvandi… - Current cancer drug …, 2016 - ingentaconnect.com
Epigenetic modifications determine phenotypic characteristics in a reversible, stable and
genotype-independent manner. Epigenetic modifications mainly encompass CpG island …
genotype-independent manner. Epigenetic modifications mainly encompass CpG island …
Cytokine storm in the pathophysiology of COVID-19: Possible functional disturbances of miRNAs
Abstract SARS-CoV-2, as the causative agent of COVID-19, is an enveloped positives-sense
single-stranded RNA virus that belongs to the Beta-CoVs sub-family. A sophisticated hyper …
single-stranded RNA virus that belongs to the Beta-CoVs sub-family. A sophisticated hyper …