Current advance of nanotechnology in diagnosis and treatment for malignant tumors

B Wang, S Hu, Y Teng, J Chen, H Wang, Y Xu… - … and Targeted Therapy, 2024 - nature.com
Cancer remains a significant risk to human health. Nanomedicine is a new multidisciplinary
field that is garnering a lot of interest and investigation. Nanomedicine shows great potential …

[HTML][HTML] RNA binding proteins (RBPs) and their role in DNA damage and radiation response in cancer

M Mehta, R Raguraman, R Ramesh… - Advanced drug delivery …, 2022 - Elsevier
Traditionally majority of eukaryotic gene expression is influenced by transcriptional and post-
transcriptional events. Alterations in the expression of proteins that act post-transcriptionally …

HuR as a molecular target for cancer therapeutics and immune-related disorders

M Majumder, P Chakraborty, S Mohan… - Advanced drug delivery …, 2022 - Elsevier
The control of eukaryotic gene expression occurs at multiple levels, from transcription to
messenger RNA processing, transport, localization, turnover, and translation. RNA-binding …

The multifaceted role of Fragile X-Related Protein 1 (FXR1) in cellular processes: an updated review on cancer and clinical applications

FA Khan, N Fang, W Zhang, S Ji - Cell Death & Disease, 2024 - nature.com
RNA-binding proteins (RBPs) modulate the expression level of several target RNAs (such as
mRNAs) post-transcriptionally through interactions with unique binding sites in the 3 …

[HTML][HTML] The short inverted repeats-induced circEXOC6B inhibits prostate cancer metastasis by enhancing the binding of RBMS1 and HuR

C Zhang, S Wang, F Chao, G Jia, X Ye, D Han, Z Wei… - Molecular Therapy, 2023 - cell.com
Circular RNAs (circRNAs) are a novel class of endogenous RNAs with a covalently closed
loop structure. Many circRNAs have been found to participate in cancer progression …

Study on the Effects of Dust Particle Size and Respiratory Intensity on the Pattern of Respiratory Particle Deposition in Humans

G Zhou, Z Liu, W Shao, B Sun, L Li, J Liu, G Li, X Lv - Indoor Air, 2024 - Wiley Online Library
Nowadays, dust exposure pollution is receiving a lot of attention due to its significant impact
on public health. To investigate the impact of dust particle size and human respiratory …

Open pocket and tighten holes: inhalable lung cancer-targeted nanocomposite for enhanced ferroptosis-apoptosis synergetic therapy

W Wang, W Wang, S Jin, F Fu, Z Huang… - Chemical Engineering …, 2023 - Elsevier
Abstract Cisplatin (DDP)-based ferroptosis-apoptosis synergetic therapy is a novel strategy
of lung cancer treatment based on the targeted induction of high oxidative stress levels in …

Inhalable iron redox cycling powered nanoreactor for amplified ferroptosis-apoptosis synergetic therapy of lung cancer

L Wu, W Wang, M Guo, F Fu, W Wang, T Sung… - Nano Research, 2024 - Springer
Fenton reaction centered ferroptosis-apoptosis synergetic therapy has emerged as a
promising tumor elimination strategy. However, the low intracellular Fenton level and …

[HTML][HTML] STAT3-specific nanocarrier for shRNA/drug dual delivery and tumor synergistic therapy

L Sun, J Sun, C Li, K Wu, Z Gu, L Guo, Y Zhou, B Han… - Bioactive Materials, 2024 - Elsevier
Non-small cell lung cancer (NSCLC) is a major disease with high incidence, low survival
rate and prone to develop drug resistance to chemotherapy. The mechanism of secondary …

Human antigen R affects the migration and invasion of human lung cancer A549 cells via regulating E-cadherin suppressor Snail

S Shan, Q Bao, G Ma, Y Yao, J Xiong… - Cellular and Molecular …, 2022 - cellmolbiol.org
Recent studies demonstrated that the progression and metastasis of lung cancer were
associated with human antigen R (HuR), a post-transcriptional RNA-binding protein that …