Galectin-2 is a prototype member of the galactoside-binding galectin family. It is
predominately expressed in the gastrointestinal tract but is also detected in several other …

Eosinophils are present in tissues, such as the respiratory tract, spleen, lymph nodes and
blood vessels. The significant presence of eosinophils in these tissues are associated with …

Human lectins are integral to maintaining microbial homeostasis on the skin, in the blood,
and at mucosal barriers. These proteins can recognize microbial glycans and inform the host …

Background The structure of human galectin-16 (Gal-16) has yet to be solved, and its
function has remained elusive. Methods X-ray crystallography was used to determine the …

Numerous articles have reported the involvement of linker in regulating bioactivity of tandem-
repeat galectins. We hypothesize that linker interacts with N/C-CRDs to regulate the …

Galectins are a family of ß-galactoside-binding lectins characterized by a unique sequence
motif in the carbohydrate recognition domain, and evolutionary and structural conservation …

Abstract Galectin-10 (Gal-10) which forms Charcot-Leyden crystals in vivo, is crucial to
regulating lymph cell function. Here, we solved the crystal structures of Gal-10 and eight …

The expression of prototype galectin‐14 (Gal‐14) in human placenta is higher than any
other galectin, suggesting that it may play a role in fetal development and regulation of …

Abstract During pregnancy, placental protein-13 (galectin-13) is highly expressed in the
placenta and fetal tissue, and less so in maternal serum that is related to pre-eclampsia. To …

Simple Summary The disaccharide lactose is a common excipient in pharmaceutical
products. In addition, the two anomers α-and β-lactose can exert immuno-modulatory effects …