Autism spectrum disorder (ASD) is a prevalent and complex neurodevelopmental disorder
which has strong genetic basis. Despite the rapidly rising incidence of autism, little is known …

Autism spectrum disorder (ASD) has a major impact on the development and social
integration of affected individuals and is the most heritable of psychiatric disorders. An …

Autism spectrum disorder (ASD) encompasses a group of multifactorial neurodevelopmental
disorders characterized by impaired social communication, social interaction and repetitive …

Neuronal networks consist of different types of neurons that all play their own role in order to
maintain proper network function. The two main types of neurons segregate in excitatory and …

Autism spectrum disorder (ASD) refers to a series of neurodevelopmental diseases
characterized by two hallmark symptoms, social communication deficits and repetitive …

Disturbances in the glutamatergic system have been increasingly documented in several
neuropsychiatric disorders, including autism spectrum disorder (ASD). Glutamate-centered …

Recent studies have revealed synaptic dysfunction to be a hallmark of various psychiatric
diseases, and that glial cells participate in synapse formation, development, and plasticity …

The genetics underlying autism spectrum disorder (ASD) is complex and heterogeneous,
and de novo variants are found in genes converging in functional biological processes …

Abstract Neuroligin-4 (NLGN4) loss-of-function mutations are associated with monogenic
heritable autism spectrum disorder (ASD) and cause alterations in both synaptic and …

The autism-associated synaptic-adhesion gene Neuroligin-4 (NLGN4) is poorly conserved
evolutionarily, limiting conclusions from Nlgn4 mouse models for human cells. Here, we …