Infection with the Gram-negative pathogen Helicobacter pylori is the most prevalent chronic
bacterial infection affecting about 50% of the human world population and is the main risk …

Gout is the most frequent form of inflammatory arthritis in the world. Its prevalence is
particularly elevated in specific geographical areas such as in the Oceania/Pacific region …

Based on high quality surgery and scientific data, scientists and surgeons are committed to
protecting patients as well as healthcare staff and hereby provide this Guidance to address …

Infection with Helicobacter pylori is established as the major risk factor for gastric cancer
development. Damage of the mucosal barrier due to H. pylori-induced inflammation …

Treatment of epithelial ovarian cancer consists of surgery plus platinum‐taxane based
chemotherapy. Neither prognostic nor predictive serum or tissue markers except BRCA1/2 …

Objectives Systemic sclerosis (SSc) is an autoimmune disease with unknown pathogenesis
manifested by inflammation, vasculopathy and fibrosis in skin and internal organs. Type I …

The Runx1 transcription factor plays an important role in tissue homeostasis through its
effects on stem/progenitor cell populations and differentiation. The effect of Runx1 on …

Transcription factors (TFs) are proteins that control the transcription of genetic information
from DNA to mRNA by binding to specific DNA sequences either on their own or with other …

Epigenetic dysregulation is a major driver of tumorigenesis. To identify tumor‐suppressive
microRNAs repressed by DNA methylation in gastric cancer (GC), we analyzed the genome …

Abnormal functioning of many cellular processes such as cell cycle, DNA repair,
angiogenesis and cell–cell adhesion has been reported in all types of cancer. In the context …