Saliva: a challenging human fluid to diagnose brain disorders with a focus on Alzheimer's disease
C Zürcher, C Humpel - Neural Regeneration Research, 2023 - journals.lww.com
Biomarkers are molecules of biological processes that help in both the diagnosis of human
diseases and in follow-up assessments of therapeutic responses. Biomarkers can be …
diseases and in follow-up assessments of therapeutic responses. Biomarkers can be …
New frontiers in autoimmune diagnostics: a systematic review on saliva testing
SG Foddai, M Radin, A Barinotti, I Cecchi… - International Journal of …, 2023 - mdpi.com
(1) Background: Immunological laboratory testing is known to be complex, and it is usually
performed in tertiary referral centers. Many criticalities affect diagnostic immunological …
performed in tertiary referral centers. Many criticalities affect diagnostic immunological …
[HTML][HTML] Salivary levels of disease-related biomarkers in the early stages of Parkinson's and Alzheimer's disease: A cross-sectional study
M Sabaei, S Rahimian, AHME Ketabforoush… - IBRO Neuroscience …, 2023 - Elsevier
Introduction Finding a non-invasive and repeatable tool has been recommended to make an
accurate diagnosis of Alzheimer's disease (AD) and Parkinson's disease (PD). Methods 70 …
accurate diagnosis of Alzheimer's disease (AD) and Parkinson's disease (PD). Methods 70 …
[PDF][PDF] Plasma amyloid-beta oligomer and phosphorylated tau: Diagnostic tools for progressive Alzheimer's disease
Introduction: Spanning the three stages of the Alzheimer's disease (AD) continuum, amyloid-
beta (Aβ40 and Aβ42) oligomers (AβO's) and tau protein constitute a set of biomarkers …
beta (Aβ40 and Aβ42) oligomers (AβO's) and tau protein constitute a set of biomarkers …
Aβ42 as a Biomarker of Alzheimer's Disease: Is Saliva a Viable Alternative to Cerebrospinal Fluid?
S Boschi, F Roveta, A Grassini, A Marcinnò, A Cermelli… - Brain Sciences, 2022 - mdpi.com
The identification of reliable biomarkers in biological fluids is paramount to optimizing the
diagnosis of Alzheimer's disease (AD). Measurement of Aβ42, t-tau, and p-tau in …
diagnosis of Alzheimer's disease (AD). Measurement of Aβ42, t-tau, and p-tau in …
[HTML][HTML] Epilepsy: Mitochondrial connections to the 'Sacred'disease
WH Moos, DV Faller, IP Glavas, I Kanara, K Kodukula… - Mitochondrion, 2023 - Elsevier
Over 65 million people suffer from recurrent, unprovoked seizures. The lack of validated
biomarkers specific for myriad forms of epilepsy makes diagnosis challenging. Diagnosis …
biomarkers specific for myriad forms of epilepsy makes diagnosis challenging. Diagnosis …
Chondroitin sulphate modified MoS2 nanoenzyme with multifunctional activities for treatment of Alzheimer's disease
J Tian, Q Peng, Y Shen, X Liu, D Li, J Li, S Guo… - International Journal of …, 2024 - Elsevier
Nano-MoS 2 exhibit oxidoreductase-like activities, and has been shown to effectively
eliminate excessive intracellular ROS and inhibit Aβ aggregation, thus demonstrating …
eliminate excessive intracellular ROS and inhibit Aβ aggregation, thus demonstrating …
Using gamma-band transcranial alternating current stimulation (tACS) to improve sleep quality and cognition in patients with mild neurocognitive disorders due to …
Background Sleep disturbances are highly prevalent in patients with age-related
neurodegenerative diseases, which severely affect cognition and even lead to accumulated …
neurodegenerative diseases, which severely affect cognition and even lead to accumulated …
How promising are the latest monoclonal antibodies targeting amyloid-β for the treatment of early Alzheimer's disease?
J Beveridge, E Kaniecki, A Naidu… - Expert Opinion on …, 2024 - Taylor & Francis
Introduction Monoclonal antibodies targeting amyloid-β are the first disease-modifying
treatments for Alzheimer disease to have received FDA-approval. There are three different …
treatments for Alzheimer disease to have received FDA-approval. There are three different …
Modulation of Alpha-Synuclein Conformational Ensemble and Aggregation Pathways by Dopamine and Related Molecules
Dopaminergic neurons are constantly threatened by the thin boundaries between functional
α-synuclein (AS) structural disorder and pathogenic aggregation, and between dopamine …
α-synuclein (AS) structural disorder and pathogenic aggregation, and between dopamine …