Diels−Alder Reaction−Aromatization Approach toward Functionalized Ring C Allocolchicinoids. Enantioselective Total Synthesis of (−)-7S-Allocolchicine

AV Vorogushin, AV Predeus, WD Wulff… - The Journal of Organic …, 2003 - ACS Publications
Allocolchicinoids are analogues of the important antimitotic compound (−)-colchicine 1. A
strategy is reported for the synthesis of ring C functionalized allocolchicinoids, which is …

β-Nitroacrylates as an Emerging, Versatile Class of Functionalized Nitroalkenes for the Synthesis of a Variety of Chemicals

R Ballini, S Gabrielli, A Palmieri - Current Organic Chemistry, 2010 - ingentaconnect.com
Modern organic synthesis requires easily obtainable synthetic building blocks that can be
manipulated without the need of severe reaction conditions and that show high chemical …

Stereoselective Synthesis of 1-Tuberculosinyl Adenosine; a Virulence Factor of Mycobacterium tuberculosis

J Buter, D Heijnen, IC Wan… - The Journal of …, 2016 - ACS Publications
Despite its status as one of the world's most prevalent and deadly bacterial pathogens,
Mycobacterium tuberculosis (Mtb) infection is not routinely diagnosed by rapid and highly …

Platinum-catalyzed α, β-unsaturated carbene formation in the formal syntheses of frondosin b and liphagal

KQ Huynh, CA Seizert, TJ Ozumerzifon… - Organic …, 2017 - ACS Publications
Formal syntheses of tetracyclic terpenoids frondosin B and liphagal are described. Both
synthetic routes rely on the use of platinum-catalyzed α, β-unsaturated carbene formation for …

Synthesis of (±)-nosyberkol (isotuberculosinol, revised structure of edaxadiene) and (±)-tuberculosinol

N Maugel, FM Mann, ML Hillwig, RJ Peters… - Organic …, 2010 - ACS Publications
Me2AlCl-catalyzed Diels− Alder reaction of N-tigloyloxazolidinone with 6, 6-dimethyl-1-
vinylcyclohexene selectively provided the exo adduct, which was converted to nosyberkol …

Convenient syntheses of tonghaosu and two thiophene substituted spiroketal enol ether natural products

Y Gao, WL Wu, B Ye, R Zhou, YL Wu - Tetrahedron letters, 1996 - Elsevier
Convenient Syntheses of Tonghaosu and Two Thiophene Substituted Spiroketal Enol Ether
Natural Products Page 1 Pergamon 0040-4039(95)02311-9 Tetrahedron Letters, Vol. 37, No. 6 …

A straightforward synthetic approach to the spiroketal-enol ethers synthesis of natural antifeeding compound tonghaosu and its analogs

Y Gao, WL Wu, YL Wu, B Ye, R Zhou - Tetrahedron, 1998 - Elsevier
Tonghaosu 1, a natural product discovered from several plants of tribe Athemdeae, is a [4.4]
spiroketal with an enediyne side-chain and shows interesting insect antifeeding activity. In …

Synthesis of Tricyclic Pterolobirin H Analogue: Evaluation of Anticancer and Anti-Inflammatory Activities and Molecular Docking Investigations

H Zentar, F Jannus, M Medina-O'Donnell… - Molecules, 2023 - mdpi.com
Pterolobirin H (3), a cassane diterpene isolated from the roots of Pterolobium macropterum,
exhibits important anti-inflammatory and anticancer properties. However, its relatively …

Enantioselective synthesis of cassane‐type furanoditerpenoids: total synthesis of sucutiniranes C and D

EN Pitsinos, I Mavridis, E Tzouma… - European Journal of …, 2020 - Wiley Online Library
The first enantioselective total synthesis of cassane‐type furanoditerpenoids featuring an
aromatic C ring and a substituted B ring is presented. The strategy employed relied on …

Diels–Alder reaction between 1, 3, 3-trisubstituted-2-vinylcyclohexenes and quinones under exceptionally mild conditions: a concise entry to the cassane-type …

E Tzouma, I Mavridis, VP Vidali, EN Pitsinos - Tetrahedron Letters, 2016 - Elsevier
Extremely mild (no metal Lewis acid catalyst, ambient temperature) and experimentally
simple (no high-pressure apparatus needed) conditions were established for the Diels …