Mechanotransduction is a process by which cells sense the mechanical properties of their
surrounding environment and adapt accordingly to perform cellular functions such as …

Years of important research has revealed that cells heavily invest in regulating their size.
Nevertheless, it has remained unclear why accurate size control is so important. Our recent …

Contractile actomyosin networks are responsible for the production of intracellular forces.
There is increasing evidence that bundles of actin filaments form interconnected and …

Motivation Due to the complexity and heterogeneity of multicellular biological systems,
mathematical models that take into account cell signalling, cell population behaviour and the …

Biofabrication techniques enable the performance of bioinspired three‐dimensional (3D)
matrices resembling primary tumors. To validate their reliability, embedded cells may …

The pathophysiology of autoimmune disorders is multifactorial, where immune cell
migration, adhesion, and lymphocyte activation play crucial roles in its progression. These …

During metastasis, cancer cells navigate through a spatially heterogeneous extracellular
matrix (ECM). Physical properties of ECM, including the degree of confinement, influence …

Junctional adhesion molecule (JAM)-A is a cell adhesion receptor localized at epithelial cell–
cell contacts with enrichment at the tight junctions. Its role during cell–cell contact formation …

Actomyosin stress fibers (SFs) support cell shape and migration by directing intracellular
tension to the extracellular matrix (ECM) via focal adhesions. Migrating cells exhibit three SF …

Groups of eukaryotic cells can coordinate their crawling motion to follow cues more
effectively, stay together, or invade new areas. This collective cell migration depends on cell …