Humans are unable to synthesise l‐ascorbic acid (L‐AA, ascorbate, vitamin C), and are thus
entirely dependent upon dietary sources to meet needs. In both plant and animal …

Vitamin C, a reducing agent and antioxidant, is a cofactor in reactions catalyzed by Cu+‐
dependent monooxygenases and Fe2+‐dependent dioxygenases. It is synthesized, in …

The field of antioxidants and free radicals is often perceived as focusing around the use of
antioxidant supplements to prevent human disease. In fact, antioxidants/free radicals …

Although ascorbic acid is an important water‐soluble antioxidant and enzyme cofactor in
plants and animals, humans and some other species do not synthesize ascorbate due to the …

The UDP-glucuronosyltransferases (UGTs) are a superfamily of membrane-bound enzymes
whose active site is localized inside the endoplasmic reticulum. Glucuronidation using …

Ascorbic acid (vitamin C) is an enzyme co-factor in eukaryotes that also plays a critical role
in protecting photosynthetic eukaryotes against damaging reactive oxygen species derived …

At present, the methods and enzymology of the UDP-glucuronosyltransferases (UGTs) lag
behind that of the cytochromes P450 (CYPs). About 15 human UGTs have been identified …

Vitamin C, a water-soluble glucose derivative, has considerable antioxidant activity in vitro,
in part because of its ease of oxidation and because the semidehydroascorbate radical …

Biosynthesis of l-ascorbate (vitamin C) occurs by different pathways in plants and mammals.
Yeast contain d-erythroascorbate, a C 5 analog of ascorbate. UDP-d-glucuronic acid is the …

Abstract Pollutants, such as Metal Trace Elements (MTEs) and organic compounds
(polycyclic aromatic hydrocarbons, pesticides), can impact DNA structure of living organisms …