Substitution of a hydrogen atom with its heavy isotope deuterium entails the addition of one
neutron to a molecule. Despite being a subtle change, this structural modification, known as …

Vitamin E is often associated with health benefits, such as antioxidant, anti-inflammatory and
cholesterol-lowering effects. These properties make its supplementation a suitable …

Tocotrienols have powerful radioprotective properties in multiple organ systems and are
promising candidates for development as clinically effective radiation countermeasures. To …

Water in tissues and cells intervenes with cellular components. The interactions of water
affect the structures, dynamics, and functions of biomolecules, including proteins, nucleic …

Considering the increasing risk of nuclear attacks worldwide, the development of develop
potent and safe radioprotective agents for nuclear emergencies is urgently needed. γ …

Garcinoic acid has been identified as an inhibitor of DNA polymerase β (pol β). However, no
structure-activity relationship (SAR) studies of garcinoic acid as a pol β inhibitor have been …

Carboxyethyl hydroxychromans (CEHCs) are natural metabolites of vitamin E (VE). Their
urinary levels can serve as useful biomarkers for the nutritional assessment of VE. Moreover …

A critical area of pharmacologic research involves the study of how a body processes a
drug, including the time course of absorption, distribution, bioavailability, metabolism, and …