Ferrocene derivatives have attracted significant interest as anticancer, antibacterial,
antifungal and antiparasitic drug candidates. Discovered in the 1990s, the two most …

The quest for alternative drugs to the well-known cisplatin and its derivatives, which are still
used in more than 50% of the treatment regimes for patients suffering from cancer, is highly …

The non-communicable disease, cancer, is one of the major causes of death across the
world and is forecast to increase by 75% to reach close to 25 million cases over the next two …

Atovaquone belongs to a naphthoquinone class of drugs and is used in combination with
proguanil (Malarone) for the treatment of acute, uncomplicated malaria caused by …

Naphthoquinones are compounds present in several families of higher plants. Their
molecular structures confer redox properties, and they are involved in multiple biological …

1, 4-Benzoquinones are ubiquitous in nature and can be synthesized by diverse strategies.
Recent developments on their synthetic methodologies, cycloaddition reactions …

1, 4-Naphthoquinones have antibacterial activity and are a promising new class of
compound that can be used to treat bacterial infections. The goal was to improve effective …

Triple-negative breast cancer (TNBC) lacks expression of estrogen receptor (ER),
progesterone receptor (PR) and HER2 gene. It comprises approximately 15-20% of breast …

Introduction Malignacies are still a major public concern worldwide and despite the intensive
search of new chemotherapeutic agents, treatment still remains a challenging issue. The …

Abstract A series of 12 novel 1, 4-naphthoquinone-1, 2, 3-triazole hybrids were designed
and synthesized through copper-catalyzed click reaction of 2-(prop-2-ynylamino) …