Over the past 10 years, the relevance of small-molecule signaling for many aspects of C.
elegans development and behavior has become apparent. One prominent group of small …

Covering: up to December 2014 Chemical ecology elucidates the nature and role of natural
products as mediators of organismal interactions. The emerging techniques that can be …

The potential of a metabolomics method to detect statistically significant perturbations in the
metabolome of an organism is enhanced by excellent analytical precision, unequivocal …

The recognition of molecular patterns associated with specific pathogens or food sources is
fundamental to ecology and plays a major role in the evolution of predator-prey relationships …

How an individual's longevity is affected by the opposite sex is still largely unclear. In the
nematode Caenorhabditis elegans, the presence of males accelerated aging and shortened …

Recent studies of animal metabolism have revealed large numbers of novel metabolites that
are involved in all aspects of organismal biology, but it is unclear to what extent …

As fundamental features of nearly all animal species, sexual dimorphisms and sex
differences have particular relevance for the development and function of the nervous …

Pheromones exchanged by conspecifics are a major class of chemical signals that can alter
behavior, physiology, and development. In particular, males and females communicate with …

Males of Caenorhabditis elegans provide a crucial practical tool in the laboratory, but, as the
rarer and more finicky sex, have not enjoyed the same depth of research attention as …

Microorganisms and plants produce a large diversity of secondary metabolites, whereas
analyses of metazoan metabolomes have yielded comparatively few types of small …