Human stem cell-based 3D in vitro angiogenesis models for preclinical drug screening applications

A Esparza, N Jimenez, EA Borrego, S Browne… - Molecular Biology …, 2024 - Springer
Vascular diseases are the underlying pathology in many life-threatening illnesses. Human
cellular and molecular mechanisms involved in angiogenesis are complex and difficult to …

Materials Characterization of Stereolithography 3D Printed Polymer to Develop a Self-Driven Microfluidic Device for Bioanalytical Applications

BL Stark, M Gamboa, A Esparza… - ACS Applied Bio …, 2024 - ACS Publications
Stereolithography (SLA) 3D printing is a rapid prototyping technique and reproducible
manufacturing platform, which makes it a useful tool to develop advanced microfluidic …

Stereolithography‐Based Polymer Additive Manufacturing Process for Microfluidics Devices: A Review

A Biswas, AK Singh, D Das - Advances in Additive …, 2024 - Wiley Online Library
Numerous fields, including biomedical research, medication delivery systems, chemical
synthesis, and diagnostics, have been transformed by microfluidics. Microfluidic devices can …

Modelling neurocardiac physiology and diseases using human pluripotent stem cells: current progress and future prospects

HF Wu, C Hamilton, H Porritt, A Winbo… - The Journal of …, 2024 - Wiley Online Library
Throughout our lifetime the heart executes cycles of contraction and relaxation to meet the
body's ever‐changing metabolic needs. This vital function is continuously regulated by the …

[HTML][HTML] Three-Dimensionally Printed Microsystems to Facilitate Flow-Based Study of Cells from Neurovascular Barriers of the Retina

A Leverant, L Oprysk, A Dabrowski, K Kyker-Snowman… - Micromachines, 2024 - mdpi.com
Rapid prototyping has produced accessible manufacturing methods that offer faster and
more cost-effective ways to develop microscale systems for cellular testing. Commercial 3D …

[PDF][PDF] Engineered 3D Cardiovascular Tissue Models Within Dynamic Microfluidic Platforms for Personalized Medicine Applications

S Natividad-Diaz, B Joddar, W Poon… - Journal of …, 2023 - par.nsf.gov
Conclusion 3D cardiovascular tissue models combined with tailored microfluidic devices or
platforms have the potential to significantly contribute to more effective drug discovery by …

Development of 3D human cardiovascular and cancer tissue model within a self-driven microfluidic platform for preclinical drug screening

AA Esparza - 2024 - search.proquest.com
Abstract According to the American Heart Association and World Health Organization,
cardiovascular diseases (CVDs) are the leading cause of death worldwide. Monolayer cell …