Boundary formation and maintenance in tissue development
The formation and maintenance of boundaries between neighbouring groups of embryonic
cells is vital for development because groups of cells with distinct functions must often be …
cells is vital for development because groups of cells with distinct functions must often be …
Molecular mechanisms of cell segregation and boundary formation in development and tumorigenesis
E Batlle, DG Wilkinson - Cold Spring Harbor …, 2012 - cshperspectives.cshlp.org
The establishment and maintenance of precisely organized tissues requires the formation of
sharp borders between distinct cell populations. The maintenance of segregated cell …
sharp borders between distinct cell populations. The maintenance of segregated cell …
The role of organizers in patterning the nervous system
C Kiecker, A Lumsden - Annual review of neuroscience, 2012 - annualreviews.org
The foundation for the anatomical and functional complexity of the vertebrate central
nervous system is laid during embryogenesis. After Spemann's organizer and its derivatives …
nervous system is laid during embryogenesis. After Spemann's organizer and its derivatives …
Midbrain-hindbrain boundary morphogenesis: at the intersection of Wnt and Fgf signaling
A constriction in the neural tube at the junction of the midbrain and hindbrain is a conserved
feature of vertebrate embryos. The constriction is a defining feature of the midbrain …
feature of vertebrate embryos. The constriction is a defining feature of the midbrain …
Cell sorting in vitro and in vivo: how are cadherins involved?
M Takeichi - Seminars in Cell & Developmental Biology, 2023 - Elsevier
Animal tissues are composed of heterogenous cells, and their sorting into different
compartments of the tissue is a pivotal process for organogenesis. Cells accomplish sorting …
compartments of the tissue is a pivotal process for organogenesis. Cells accomplish sorting …
Mouse Fgf8‐Cre‐LacZ lineage analysis defines the territory of the postnatal mammalian isthmus
The isthmus is recognized as the most rostral segment of the hindbrain in non‐mammalian
vertebrates. In mammalian embryos, transient Fgf8 expression defines the developing …
vertebrates. In mammalian embryos, transient Fgf8 expression defines the developing …
The eye organizes neural crest cell migration
T Langenberg, A Kahana, JA Wszalek… - … dynamics: an official …, 2008 - Wiley Online Library
In the anterior vertebrate head, a population of neural crest cells (NCCs) migrates to the
periocular mesenchyme and makes critical contributions to the developing eye and orbit …
periocular mesenchyme and makes critical contributions to the developing eye and orbit …
Modeling of Wnt-mediated tissue patterning in vertebrate embryogenesis
J Rosenbauer, C Zhang, B Mattes… - PLOS Computational …, 2020 - journals.plos.org
During embryogenesis, morphogens form a concentration gradient in responsive tissue,
which is then translated into a spatial cellular pattern. The mechanisms by which …
which is then translated into a spatial cellular pattern. The mechanisms by which …
Imaging and multi-omics datasets converge to define different neural progenitor origins for ATRT-SHH subgroups
MJ Lobón-Iglesias, M Andrianteranagna… - Nature …, 2023 - nature.com
Atypical teratoid rhabdoid tumors (ATRT) are divided into MYC, TYR and SHH subgroups,
suggesting diverse lineages of origin. Here, we investigate the imaging of human ATRT at …
suggesting diverse lineages of origin. Here, we investigate the imaging of human ATRT at …
Gbx2 and Fgf8 are sequentially required for formation of the midbrain-hindbrain compartment boundary
NA Sunmonu, K Li, Q Guo, JYH Li - Development, 2011 - journals.biologists.com
In vertebrates, the common expression border of two homeobox genes, Otx2 and Gbx2,
demarcates the prospective midbrain-hindbrain border (MHB) in the neural plate at the end …
demarcates the prospective midbrain-hindbrain border (MHB) in the neural plate at the end …