Boundary formation and maintenance in tissue development

C Dahmann, AC Oates, M Brand - Nature Reviews Genetics, 2011 - nature.com
The formation and maintenance of boundaries between neighbouring groups of embryonic
cells is vital for development because groups of cells with distinct functions must often be …

Molecular mechanisms of cell segregation and boundary formation in development and tumorigenesis

E Batlle, DG Wilkinson - Cold Spring Harbor …, 2012 - cshperspectives.cshlp.org
The establishment and maintenance of precisely organized tissues requires the formation of
sharp borders between distinct cell populations. The maintenance of segregated cell …

The role of organizers in patterning the nervous system

C Kiecker, A Lumsden - Annual review of neuroscience, 2012 - annualreviews.org
The foundation for the anatomical and functional complexity of the vertebrate central
nervous system is laid during embryogenesis. After Spemann's organizer and its derivatives …

Midbrain-hindbrain boundary morphogenesis: at the intersection of Wnt and Fgf signaling

HC Gibbs, A Chang-Gonzalez, W Hwang… - Frontiers in …, 2017 - frontiersin.org
A constriction in the neural tube at the junction of the midbrain and hindbrain is a conserved
feature of vertebrate embryos. The constriction is a defining feature of the midbrain …

Cell sorting in vitro and in vivo: how are cadherins involved?

M Takeichi - Seminars in Cell & Developmental Biology, 2023 - Elsevier
Animal tissues are composed of heterogenous cells, and their sorting into different
compartments of the tissue is a pivotal process for organogenesis. Cells accomplish sorting …

Mouse Fgf8‐Cre‐LacZ lineage analysis defines the territory of the postnatal mammalian isthmus

C Watson, T Shimogori, L Puelles - Journal of Comparative …, 2017 - Wiley Online Library
The isthmus is recognized as the most rostral segment of the hindbrain in non‐mammalian
vertebrates. In mammalian embryos, transient Fgf8 expression defines the developing …

The eye organizes neural crest cell migration

T Langenberg, A Kahana, JA Wszalek… - … dynamics: an official …, 2008 - Wiley Online Library
In the anterior vertebrate head, a population of neural crest cells (NCCs) migrates to the
periocular mesenchyme and makes critical contributions to the developing eye and orbit …

Modeling of Wnt-mediated tissue patterning in vertebrate embryogenesis

J Rosenbauer, C Zhang, B Mattes… - PLOS Computational …, 2020 - journals.plos.org
During embryogenesis, morphogens form a concentration gradient in responsive tissue,
which is then translated into a spatial cellular pattern. The mechanisms by which …

Imaging and multi-omics datasets converge to define different neural progenitor origins for ATRT-SHH subgroups

MJ Lobón-Iglesias, M Andrianteranagna… - Nature …, 2023 - nature.com
Atypical teratoid rhabdoid tumors (ATRT) are divided into MYC, TYR and SHH subgroups,
suggesting diverse lineages of origin. Here, we investigate the imaging of human ATRT at …

Gbx2 and Fgf8 are sequentially required for formation of the midbrain-hindbrain compartment boundary

NA Sunmonu, K Li, Q Guo, JYH Li - Development, 2011 - journals.biologists.com
In vertebrates, the common expression border of two homeobox genes, Otx2 and Gbx2,
demarcates the prospective midbrain-hindbrain border (MHB) in the neural plate at the end …