Glioblastoma (GBM) is known as a tumor type, which arises from astrocytes. Several studies
indicated that GBM tumor cells are malignant. This is because of the fact that they consist of …

Glioblastoma multiforme (GBM) is the most common and lethal cancer of the adult brain,
remaining incurable with a median survival time of only 15 months. In an effort to identify …

The comprehensive lncRNA expression signature in glioma has not yet been fully
elucidated. We performed a high-throughput microarray to detect the ncRNA expression …

Background Emerging evidences have indicated that long noncoding RNAs (lncRNAs) play
essential roles in the development and progression of cancers. Dysregulation of lncRNA …

Wnt signaling pathways and microRNAs (miRNAs) are critical regulators of development.
Aberrant Wnt signaling pathways and miRNA levels lead to developmental defects and …

Although the combination of etoposide (VP16) and cisplatin (DDP) is widely used as a first-
line treatment for advanced-stage small-cell lung cancer (SCLC), chemoresistance limits its …

Despite, melatonin is mainly known as a regulatory factor for circadian rhythm, its notable
role in other fundamental biological processes, such as redox homeostasis and …

Background Glioma metastasis, invasion, epithelial-mesenchymal transition (EMT) and
chemoresistance indicate poor prognosis. Accumulating evidence reveals that Notch1 is an …

Cardiovascular diseases and cancers are the leading causes of morbidity and mortality in
the world. MicroRNAs (miRNAs) are short non-coding RNAs that primarily repress target …

Glioblastoma (GB) is a highly aggressive cancer of the central nervous system, occurring in
the brain or spinal cord. Many factors such as angiogenesis are associated with GB …