Challenges and best practices in omics benchmarking

TG Brooks, NF Lahens, A Mrčela, GR Grant - Nature Reviews Genetics, 2024 - nature.com
Technological advances enabling massively parallel measurement of biological features—
such as microarrays, high-throughput sequencing and mass spectrometry—have ushered in …

The power and promise of RNA‐seq in ecology and evolution

EV Todd, MA Black, NJ Gemmell - Molecular ecology, 2016 - Wiley Online Library
Reference is regularly made to the power of new genomic sequencing approaches. Using
powerful technology, however, is not the same as having the necessary power to address a …

The potential role and rationale for treatment of heart failure with sodium–glucose co‐transporter 2 inhibitors

J Butler, CE Hamo, G Filippatos… - European journal of …, 2017 - Wiley Online Library
Heart failure (HF) and type 2 diabetes mellitus (T2DM) are both growing public health
concerns contributing to major medical and economic burdens to society. T2DM increases …

Comparative Transcriptome Analysis between Low- and High-Cadmium-Accumulating Genotypes of Pakchoi (Brassica chinensis L.) in Response to Cadmium Stress

Q Zhou, JJ Guo, CT He, C Shen… - … science & technology, 2016 - ACS Publications
To reduce cadmium (Cd) pollution of food chains, screening and breeding of low-Cd-
accumulating cultivars are the focus of much study. Two previously identified genotypes, a …

On the utility of RNA sample pooling to optimize cost and statistical power in RNA sequencing experiments

A Takele Assefa, J Vandesompele, O Thas - BMC genomics, 2020 - Springer
Background In gene expression studies, RNA sample pooling is sometimes considered
because of budget constraints or lack of sufficient input material. Using microarray …

An evaluation of RNA-seq differential analysis methods

D Li, MS Zand, TD Dye, ML Goniewicz, I Rahman… - PLoS …, 2022 - journals.plos.org
RNA-seq is a high-throughput sequencing technology widely used for gene transcript
discovery and quantification under different biological or biomedical conditions. A …

Emerging genetic tools to investigate molecular pathways related to heat stress in chickens: A review

F Perini, F Cendron, G Rovelli, C Castellini… - Animals, 2020 - mdpi.com
Simple Summary New genomic tools have been used as an instrument in order to assess
the molecular pathway involved in heat stress resistance. Local chicken breeds have a …

MIR503HG loss promotes endothelial-to-mesenchymal transition in vascular disease

JP Monteiro, J Rodor, A Caudrillier, JP Scanlon… - Circulation …, 2021 - Am Heart Assoc
Rationale: Endothelial-to-mesenchymal transition (EndMT) is a dynamic biological process
involved in pathological vascular remodeling. However, the molecular mechanisms that …

Chronic exposure to glyphosate induces transcriptional changes in honey bee larva: A toxicogenomic study

DE Vázquez, JM Latorre-Estivalis, S Ons… - Environmental …, 2020 - Elsevier
The honey bee Apis mellifera is the most abundant managed pollinator in diverse crops
worldwide. Consequently, it is exposed to a plethora of environmental stressors, among …

Noncoding RNAs serve as diagnosis and prognosis biomarkers for hepatocellular carcinoma

C Tan, J Cao, L Chen, X Xi, S Wang, Y Zhu… - Clinical …, 2019 - academic.oup.com
BACKGROUND Reliable noninvasive biomarkers for hepatocellular carcinoma (HCC)
diagnosis and prognosis are urgently needed. We explored the potential of not only …