Challenges and best practices in omics benchmarking
TG Brooks, NF Lahens, A Mrčela, GR Grant - Nature Reviews Genetics, 2024 - nature.com
Technological advances enabling massively parallel measurement of biological features—
such as microarrays, high-throughput sequencing and mass spectrometry—have ushered in …
such as microarrays, high-throughput sequencing and mass spectrometry—have ushered in …
The power and promise of RNA‐seq in ecology and evolution
Reference is regularly made to the power of new genomic sequencing approaches. Using
powerful technology, however, is not the same as having the necessary power to address a …
powerful technology, however, is not the same as having the necessary power to address a …
The potential role and rationale for treatment of heart failure with sodium–glucose co‐transporter 2 inhibitors
J Butler, CE Hamo, G Filippatos… - European journal of …, 2017 - Wiley Online Library
Heart failure (HF) and type 2 diabetes mellitus (T2DM) are both growing public health
concerns contributing to major medical and economic burdens to society. T2DM increases …
concerns contributing to major medical and economic burdens to society. T2DM increases …
Comparative Transcriptome Analysis between Low- and High-Cadmium-Accumulating Genotypes of Pakchoi (Brassica chinensis L.) in Response to Cadmium Stress
Q Zhou, JJ Guo, CT He, C Shen… - … science & technology, 2016 - ACS Publications
To reduce cadmium (Cd) pollution of food chains, screening and breeding of low-Cd-
accumulating cultivars are the focus of much study. Two previously identified genotypes, a …
accumulating cultivars are the focus of much study. Two previously identified genotypes, a …
On the utility of RNA sample pooling to optimize cost and statistical power in RNA sequencing experiments
A Takele Assefa, J Vandesompele, O Thas - BMC genomics, 2020 - Springer
Background In gene expression studies, RNA sample pooling is sometimes considered
because of budget constraints or lack of sufficient input material. Using microarray …
because of budget constraints or lack of sufficient input material. Using microarray …
An evaluation of RNA-seq differential analysis methods
RNA-seq is a high-throughput sequencing technology widely used for gene transcript
discovery and quantification under different biological or biomedical conditions. A …
discovery and quantification under different biological or biomedical conditions. A …
Emerging genetic tools to investigate molecular pathways related to heat stress in chickens: A review
Simple Summary New genomic tools have been used as an instrument in order to assess
the molecular pathway involved in heat stress resistance. Local chicken breeds have a …
the molecular pathway involved in heat stress resistance. Local chicken breeds have a …
MIR503HG loss promotes endothelial-to-mesenchymal transition in vascular disease
JP Monteiro, J Rodor, A Caudrillier, JP Scanlon… - Circulation …, 2021 - Am Heart Assoc
Rationale: Endothelial-to-mesenchymal transition (EndMT) is a dynamic biological process
involved in pathological vascular remodeling. However, the molecular mechanisms that …
involved in pathological vascular remodeling. However, the molecular mechanisms that …
Chronic exposure to glyphosate induces transcriptional changes in honey bee larva: A toxicogenomic study
The honey bee Apis mellifera is the most abundant managed pollinator in diverse crops
worldwide. Consequently, it is exposed to a plethora of environmental stressors, among …
worldwide. Consequently, it is exposed to a plethora of environmental stressors, among …
Noncoding RNAs serve as diagnosis and prognosis biomarkers for hepatocellular carcinoma
C Tan, J Cao, L Chen, X Xi, S Wang, Y Zhu… - Clinical …, 2019 - academic.oup.com
BACKGROUND Reliable noninvasive biomarkers for hepatocellular carcinoma (HCC)
diagnosis and prognosis are urgently needed. We explored the potential of not only …
diagnosis and prognosis are urgently needed. We explored the potential of not only …