Resembling soft tissues, stretchable hydrogels are promising biomaterials for many
biomedical applications due to their excellent mechanical robustness. However …

The first general protocol for the synthesis of 1, 3-benzothiazepine derivatives was
established. With the aid of bench-stable hypervalent iodine promoter fluoro-HTIB, these …

Methoxycarbonylation of a variety of amines into the corresponding methyl carbamates was
accomplished by allowing them to react with (trimethylsilyl) diazomethane TMSCHN2 under …

The pyrrole-tethered veratroles 16 and 27 each engage in PIFA-induced oxidative
cyclization reactions to give compounds 22 and 29, respectively, which incorporate a key …

Nevirapine (11-cyclopropyl-5, 11-dihydro-4-methyl-6H-dipyrido [3, 2-b: 2′, 3′-e][1, 4]
diazepin-6-one, NVP) is a non-nucleoside HIV-1 reverse transcriptase inhibitor used to …

The influence of side‐chain structure on the mode of reaction of ortho‐quinone amines has
been investigated with a view, ultimately, to developing potential methods of therapeutic …

Methyl 6-(2-acetylaminoethyl)-4-hydroxy-benzothiazole-2-carboxylate, the benzothiazole
core of the natural product violatinctamine, was prepared in a biomimetic oxidative route …

Publisher Summary This chapter focuses on heterocycle-forming reactions of 1, 2-
benzoquinones (ortho-quinones), systematically analyzing the modes of reaction of ortho …

The influence of N-substituents and chain length on the mode and rate of intramolecular
reaction of ortho-quinone amines is reviewed. These reactions have been the subject of a …

The influence of N-substituents on the mode of reaction of ortho-quinones generated by
oxidation of N-substituted dopamine derivatives 8 has been studied. Ortho-quinones with …