Alternative animal models of aging research

S Holtze, E Gorshkova, S Braude… - Frontiers in Molecular …, 2021 - frontiersin.org
Most research on mechanisms of aging is being conducted in a very limited number of
classical model species, ie, laboratory mouse (Mus musculus), rat (Rattus norvegicus …

Post-translational modification regulates formation and cargo-loading of extracellular vesicles

JM Carnino, K Ni, Y Jin - Frontiers in Immunology, 2020 - frontiersin.org
Accumulating evidence suggests that post-translational modifications (PTMs) regulate the
selective encapsulation of non-coding RNA molecules into extracellular vesicles (EVs) and …

Extracellular vesicles in veterinary medicine

V Moccia, A Sammarco, L Cavicchioli, M Castagnaro… - Animals, 2022 - mdpi.com
Simple Summary Extracellular vesicles (EVs) are small vesicles released by human and
animal cells, parasites, microorganisms, and plants. They travel within bodily fluids …

Peptidylarginine deiminase isozyme-specific PAD2, PAD3 and PAD4 inhibitors differentially modulate extracellular vesicle signatures and cell invasion in two …

P Uysal-Onganer, A MacLatchy, R Mahmoud… - International journal of …, 2020 - mdpi.com
Glioblastoma multiforme (GBM) is an aggressive adult brain tumour with poor prognosis.
Roles for peptidylarginine deiminases (PADs) in GBM have recently been highlighted. Here …

[HTML][HTML] Inhibiting CDK4/6 in pancreatic ductal adenocarcinoma via microRNA-21

M Mortoglou, F Miralles, RR Mould, D Sengupta… - European Journal of …, 2023 - Elsevier
Pancreatic ductal adenocarcinoma (PDAC) is one of the most aggressive malignancies, with
a 5-year survival rate of 5–10%. The high mortality rate is due to the asymptomatic …

Putative roles for peptidylarginine deiminases in COVID-19

ED Arisan, P Uysal-Onganer, S Lange - International Journal of …, 2020 - mdpi.com
Peptidylarginine deiminases (PADs) are a family of calcium-regulated enzymes that are
phylogenetically conserved and cause post-translational deimination/citrullination …

RNA and Protein Delivery By Cell‐Secreted and Bioengineered Extracellular Vesicles

BZ Wang, LJ Luo… - Advanced healthcare …, 2022 - Wiley Online Library
Extracellular vesicles (EVs) are carriers of biological signals through export and delivery of
RNAs and proteins. Of increasing interest is the use of EVs as a platform for delivery of …

The hypoxia adaptation of small mammals to plateau and underground burrow conditions

M Li, D Pan, H Sun, L Zhang, H Cheng… - Animal Models and …, 2021 - Wiley Online Library
Oxygen is one of the important substances for the survival of most life systems on the earth,
and plateau and underground burrow systems are two typical hypoxic environments. Small …

Preliminary investigations into the effect of exercise-induced muscle damage on systemic extracellular vesicle release in trained younger and older men

Y Kyriakidou, I Cooper, I Kraev, S Lange… - Frontiers in …, 2021 - frontiersin.org
Background: Exercise-induced muscle damage (EIMD) results in transient muscle
inflammation, strength loss, and muscle soreness and may cause subsequent exercise …

Metabarcoding Reveals Temporal Patterns of Community Composition and Realized Thermal Niches of Thalassiosira Spp. (Bacillariophyceae) from the Narragansett …

TA Rynearson, SA Flickinger, DN Fontaine - Biology, 2020 - mdpi.com
Diatoms generate nearly half of marine primary production and are comprised of a diverse
array of species that are often morphologically cryptic or difficult to identify using light …